Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel
Fong, E.L.S. ; Toh, T.B. ; Lin, Q.X.X. ; Liu, Z. ; Hooi, L. ; Rashid, M.B.M.A. ; Benoukraf, T. ; Chow, E.K.-H. ; Huynh, T.H. ; Yu, H.
Lin, Q.X.X.
Liu, Z.
Rashid, M.B.M.A.
Huynh, T.H.
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Alternative Title
Abstract
This data article presents datasets associated with the research article entitled “Generation of matched patient-derived xenograft in vitro–in vivo models using 3D macroporous hydrogels for the study of liver cancer” (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes. © 2018 The Authors
Keywords
Source Title
Data in Brief
Publisher
Elsevier Inc.
Series/Report No.
Collections
Rights
Attribution 4.0 International
Date
2018
DOI
10.1016/j.dib.2018.03.045
Type
Data Paper