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Pseudo-random single photon counting system: A high speed implementation and its applications

Zhang, Q.
Chen, N.
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Abstract
As a new time-resolved method which combines the spread spectrum time-resolved method with single photon counting, pseudo-random single photon counting (PRSPC) has been proved to have the potential for high speed data acquisition due to high count rate achievable. A continuous wave laser modulated by a pseudo-random bit sequence is used to illuminate the sample, while single photon counting is used to build up the optical signal in response to the excitation. Periodic cross-correlation is performed to retrieve the temporal profile. Besides the high count rate, PRSPC also offers low system cost and portability which are not with the conventional time-correlated single photon counting (TCSPC). In this paper, we report a high speed PRSPC system that can be used for real time acquisition of the temporal spread function (TPSF) of diffuse photons. We also present preliminary experimental work of human blood glucose testing studies by utilizing the PRSPC system. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).
Keywords
pseudo-random bit sequence, single photon counting, Time-resolved
Source Title
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Publisher
Series/Report No.
Organizational Units
Organizational Unit
BIOENGINEERING
dept
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Date
2011
DOI
10.1117/12.874390
Type
Conference Paper
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