Gastric carcinoma: imaging diagnosis, staging and assessment of treatment response
Hallinan, J.T.P.D. Venkatesh, S.K.
Hallinan, J.T.P.D.
Citations
Altmetric:
Alternative Title
Abstract
Gastric carcinoma (GC) is one of the most common causes of cancer-related death worldwide. Surgical resection is the only cure available and is dependent on the GC stage at presentation, which incorporates depth of tumor invasion, extent of lymph node and distant metastases. Accurate preoperative staging is therefore essential for optimal surgical management with consideration of preoperative and/or postoperative chemotherapy. Multidetector computed tomography (MDCT) with its ability to assess tumor depth, nodal disease and metastases is the preferred technique for staging GC. Endoscopic ultrasonography is more accurate for assessing the depth of wall invasion in early cancer, but is limited in the assessment of advanced local or stenotic cancer and detection of distant metastases. Magnetic resonance imaging (MRI), although useful for staging, is not proven to be effective. Positron emission tomography (PET) is most useful for detecting and characterizing distant metastases. Both MDCT and PET are useful for assessment of treatment response following preoperative chemotherapy and for detection of recurrence after surgical resection. This review article discusses the usefulness of imaging modalities for detecting, staging and assessing treatment response for GC and the potential role of newer applications including CT volumetry, virtual gastroscopy and perfusion CT in the management of GC. © 2013 International Cancer Imaging Society.
Keywords
Computed tomography, Endoscopic ultrasonography, Gastric carcinoma, Magnetic resonance imaging, Positron emission tomography
Source Title
Cancer Imaging
Publisher
Series/Report No.
Collections
Rights
Date
2013
DOI
10.1102/1470-7330.2013.0023
Type
Review