Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess
Molton J.S. Chee Y.L. Hennedige T.P. Venkatesh S.K. Archuleta S.
Venkatesh S.K.
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Alternative Title
Abstract
Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis. Copyright: © 2015 Molton et al.
Keywords
abscess drainage, adult, age, Article, computer assisted tomography, controlled study, deep vein thrombosis, diabetes mellitus, disease association, female, gender, human, immobility, inferior vena cava thrombosis, Klebsiella pneumoniae, Klebsiella pneumoniae infection, liver abscess, liver vein thrombosis, lung embolism, major clinical study, male, portal vein thrombosis, retrospective study, thrombophlebitis, complication, isolation and purification, Klebsiella infection, liver abscess, liver vein, microbiology, middle aged, pathology, thrombophlebitis, anticoagulant agent, Anticoagulants, Female, Hepatic Veins, Humans, Klebsiella Infections, Klebsiella pneumoniae, Liver Abscess, Male, Middle Aged, Retrospective Studies, Thrombophlebitis
Source Title
PLoS ONE
Publisher
Series/Report No.
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Rights
Attribution 4.0 International
Date
2015
DOI
10.1371/journal.pone.0140129
Type
Article