Surface modification of polypyrrole films via grafting of poly(ethylene glycol) for improved biocompatibility
Lim, V.W.L. Kang, E.T. Neoh, K.G.
Lim, V.W.L.
Citations
Altmetric:
Alternative Title
Abstract
Modification of polypyrrole (PPY) films in the salt and deprotonated forms was carried out via UV-induced surface graft copolymerization with methoxy-poly(ethylene glycol) monomethacrylate (PEGMA) macromonomer. Contact angle and X-ray photoelectron spectroscopy (XPS) measurements were used to characterize the surface-modified PPY films. The biocompatibility of the PEGMA polymer-modified films was compared to that of the pristine films based on their ability to reduce protein adsorption, platelet adhesion and blood coagulation (antithrombogenicity property). The studies performed showed that the graft-modified films exhibited excellent biocompatibility based on all three criteria.
Keywords
Biocompatibility, Graft copolymerization, PEGMA, Polypyrrole, XPS
Source Title
Synthetic Metals
Publisher
Series/Report No.
Collections
Rights
Date
2001-03-15
DOI
10.1016/S0379-6779(00)01028-6
Type
Article