1. ScholarBank@NUS

Sebastian Schaefer

rp33743

Collaboration Map View Statistics Email Alert RSS Feed

Profile

Full Name
Sebastian Schaefer
Variants
Sebastian Schafer
Schafer S.
 
Main Affiliation
 
Faculty
 
Email
gmssseb@nus.edu.sg
 

Publications

Refined By:
Type:  Article

Results 1-18 of 18 (Search time: 0.262 seconds).

Issue DateTitleAuthor(s)
19-Apr-2021Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunityLee, CQE ; Kerouanton, B ; Chothani, S ; Zhang, S ; Chen, Y; Mantri, CK ; Hock, DH; Lim, R ; Nadkarni, R; Huynh, VT; Lim, D; Chew, WL ; Zhong, FL; Stroud, DA; Schafer, S ; Tergaonkar, V ; St John, AL ; Rackham, OJL ; Ho, L 
22016Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition GenesPua C.J.; Bhalshankar J.; Miao K.; Walsh R.; John S.; Lim S.Q.; Chow K.; Buchan R.; Soh B.Y.; Lio P.M.; Lim J.; Schafer S. ; Lim J.Q.; Tan P. ; Whiffin N.; Barton P.J.; Ware J.S.; Cook S.A. 
32013Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathyArndt A.-K.; Schafer S. ; Drenckhahn J.-D.; Sabeh M.K.; Plovie E.R.; Caliebe A.; Klopocki E.; Musso G.; Werdich A.A.; Kalwa H.; Heinig M.; Padera R.F.; Wassilew K.; Bluhm J.; Harnack C.; Martitz J.; Barton P.J.; Greutmann M.; Berger F.; Hubner N.; Siebert R.; Kramer H.-H.; Cook S.A. ; Macrae C.A.; Klaassen S.
44-Jan-2021Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASHDong, Jinrui ; Viswanathan, Sivakumar ; Adami, Eleonora ; Singh, Brijesh K ; Chothani, Sonia P ; Ng, Benjamin; Lim, Wei Wen ; Zhou, Jin ; Tripathi, Madhulika ; Ko, Nicole SJ; Shekeran, Shamini G; Tan, Jessie ; Lim, Sze Yun ; Wang, Mao; Lio, Pei Min; Yen, Paul M ; Schafer, Sebastian ; Cook, Stuart A ; Widjaja, Anissa A 
52017IL-11 is a crucial determinant of cardiovascular fibrosisSchafer S. ; Viswanathan S. ; Widjaja A.A. ; Lim W.-W.; Moreno-Moral A. ; DeLaughter D.M.; Ng B.; Patone G.; Chow K.; Khin E. ; Tan J.; Chothani S.P.; Ye L.; Rackham O.J.L. ; Ko N.S.J.; Sahib N.E. ; Pua C.J.; Zhen N.T.G.; Xie C.; Wang M. ; Maatz H.; Lim S.; Saar K.; Blachut S.; Petretto E. ; Schmidt S.; Putoczki T.; Guimarães-Camboa N.; Wakimoto H.; Van Heesch S.; Sigmundsson K. ; Lim S.L.; Soon J.L. ; Chao V.T.T. ; Chua Y.L.; Tan T.E.; Evans S.M.; Loh Y.J.; Jamal M.H.; Ong K.K.; Chua K.C.; Ong B.-H.; Chakaramakkil M.J.; Seidman J.G.; Seidman C.E.; Hubner N.; Sin K.Y.K.; Cook S.A. 
68-May-2019Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Non-Alcoholic Steatohepatitis.Widjaja, Anissa A ; Singh, Brijesh K ; Adami, Eleonora ; Viswanathan, Sivakumar ; Dong, Jinrui ; D'Agostino, Giuseppe A ; Ng, Benjamin ; Lim, Wei Wen ; Tan, Jessie ; Paleja, Bhairav S; Tripathi, Madhulika ; Lim, Sze Yun; Shekeran, Shamini Guna ; Chothani, Sonia P; Rabes, Anne; Sombetzki, Martina; Bruinstroop, Eveline ; Min, Lio Pei; Sinha, Rohit A; Albani, Salvatore ; Yen, Paul M ; Schafer, Sebastian ; Cook, Stuart A 
72015Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and diseaseRoberts A.M.; Ware J.S.; Herman D.S.; Schafer S. ; Baksi J.; Bick A.G.; Buchan R.J.; Walsh R.; John S.; Wilkinson S.; Mazzarotto F.; Felkin L.E.; Gong S.; Macarthur J.A.L.; Cunningham F.; Flannick J.; Gabriel S.B.; Altshuler D.M.; MacDonald P.S.; Heinig M.; Keogh A.M.; Hayward C.S.; Banner N.R.; Pennell D.J.; O'Regan D.P.; San T.R. ; De Marvao A.; Dawes T.J.W.; Gulati A.; Birks E.J.; Yacoub M.H.; Radke M.; Gotthardt M.; Wilson J.G.; O'Donnell C.J.; Prasad S.K.; Barton P.J.R.; Fatkin D.; Hubner N.; Seidman J.G.; Seidman C.E.; Cook S.A. 
82020Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse modelsLim, W.-W.; Corden, B. ; Ng, B. ; Vanezis, K.; D’Agostino, G.; Widjaja, A.A. ; Song, W.-H.; Xie, C.; Su, L.; Kwek, X.-Y.; Tee, N.G.Z.; Dong, J. ; Ko, N.S.J.; Wang, M. ; Pua, C.J.; Jamal, M.H.; Soh, B.; Viswanathan, S. ; Schafer, S. ; Cook, S.A. 
99-Jun-2021Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injuryWidjaja, Anissa A ; Dong, Jinrui ; Adami, Eleonora ; Viswanathan, Sivakumar; Ng, Benjamin; Pakkiri, Leroy S; Chothani, Sonia P; Singh, Brijesh K ; Lim, Wei Wen ; Zhou, Jin; Shekeran, Shamini G; Tan, Jessie ; Lim, Sze Yun; Goh, Joyce; Wang, Mao; Holgate, Robert; Hearn, Arron; Felkin, Leanne E; Yen, Paul M; Dear, James W; Drum, Chester L ; Schafer, Sebastian ; Cook, Stuart A 
102014RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processingMaatz H.; Jens M.; Liss M.; Schafer S. ; Heinig M.; Kirchner M.; Adami E.; Rintisch C.; Dauksaite V.; Radke M.H.; Selbach M.; Barton P.J.R.; Cook S.A. ; Rajewsky N.; Gotthardt M.; Landthaler M.; Hubner N.
118-Jul-2021Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosisNg, Benjamin ; Widjaja, Anissa A. ; Viswanathan, Sivakumar ; Dong, Jinrui ; Chothani, Sonia P. ; Lim, Stella ; Shekeran, Shamini G. ; Tan, Jessie ; McGregor, Narelle E.; Walker, Emma C.; Sims, Natalie A.; Schafer, Sebastian ; Cook, Stuart A. 
125-Dec-2022Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney diseaseWidjaja, Anissa A ; Viswanathan, Sivakumar ; Shekeran, Shamini G ; Adami, Eleonora ; Lim, Wei-Wen ; Chothani, Sonia ; Tan, Jessie ; Goh, Joyce Wei Ting ; Chen, Hui Mei; Lim, Sze Yun ; Boustany-Kari, Carine M; Hawkins, Julie; Petretto, Enrico ; Huebner, Norbert ; Schafer, Sebastian ; Coffman, Thomas M ; Cook, Stuart A 
1326-Aug-2021The pro-regenerative effects of hyperil6 in drug induced liver injury are unexpectedly due to competitive inhibition of il11 signalingDong, Jinrui ; Viswanathan, Sivakumar ; Adami, Eleonora ; Schafer, Sebastian ; Kuthubudeen, Fathima F. ; Widjaja, Anissa A. ; Cook, Stuart A. 
142015Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathyHinson J.T.; Chopra A.; Nafissi N.; Polacheck W.J.; Benson C.C.; Swist S.; Gorham J.; Yang L.; Schafer S. ; Sheng C.C.; Haghighi A.; Homsy J.; Hubner N.; Church G.; Cook S.A. ; Linke W.A.; Chen C.S.; Seidman J.G.; Seidman C.E.
152019Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivoZhou J ; Ng B. ; Ko N.S.J. ; Fiedler L.R.; Khin E. ; Lim A. ; Sahib N.E. ; Wu Y. ; Chothani S.P.; Schafer S. ; Bay B.-H. ; Sinha R.A. ; Cook S.A.; Yen P.M. 
162017Titin-truncating variants affect heart function in disease cohorts and the general populationSchafer S. ; De Marvao A.; Adami E.; Fiedler L.R. ; Ng B.; Khin E. ; Rackham O.J.L. ; Van Heesch S.; Pua C.J.; Kui M.; Walsh R.; Tayal U.; Prasad S.K.; Dawes T.J.W.; Ko N.S.J.; Sim D.; Chan L.L.H.; Chin C.W.L. ; Mazzarotto F.; Barton P.J.; Kreuchwig F.; De Kleijn D.P.V. ; Totman T. ; Biffi C.; Tee N.; Rueckert D.; Schneider V.; Faber A.; Regitz-Zagrosek V.; Seidman J.G.; Seidman C.E.; Linke W.A.; Kovalik J.-P. ; O'Regan D.; Ware J.S.; Hubner N.; Cook S.A. 
172017Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac functionMcDermott-Roe C.; Leleu M.; Rowe G.C.; Palygin O.; Bukowy J.D.; Kuo J.; Rech M.; Hermans-Beijnsberger S.; Schaefer S. ; Adami E. ; Creemers E.E.; Heinig M.; Schroen B.; Arany Z.; Petretto E. ; Geurts A.M.
182020Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in miceLim, W.-W.; Ng, B. ; Widjaja, A. ; Xie, C.; Su, L.; Ko, N. ; Lim, S.-Y.; Kwek, X.-Y.; Lim, S. ; Cook, S.A. ; Schafer, S.