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Alan Prem Kumar

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Full Name
Alan Prem Kumar
Variants
Kumar, A.P.
Kumar, A.
Prem Kumar, A.
Kumar, Alan Prem Rem
 
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Faculty
 
Email
apkumar@nus.edu.sg
 
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Publications

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Type:  Article

Results 1-20 of 99 (Search time: 0.013 seconds).

Issue DateTitleAuthor(s)
11-Jul-20222,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGF beta-Driven Signaling Cascades in Colon Cancer CellsJung, Young Yun; Mohan, Chakrabhavi Dhananjaya; Eng, Huiyan; Narula, Acharan S; Namjoshi, Ojas A; Blough, Bruce E; Rangappa, Kanchugarakoppal S; Sethi, Gautam ; Kumar, Alan Prem ; Ahn, Kwang Seok
22017A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinomaDai X.; Wang L. ; Deivasigamni A.; Looi C.Y.; Karthikeyan C.; Trivedi P.; Chinnathambi A.; Alharbi S.A.; Arfuso F.; Dharmarajan A.; Goh B.C. ; Hui K.M. ; Kumar A.P. ; Mustafa M.R.; Sethi G. 
32019A novel small-molecule inhibitor of trefoil factor 3 (TFF3) potentiates MEK1/2 inhibition in lung adenocarcinomaZhang, M.; Wang, B.; Chong, Q.-Y. ; Pandey, V.; Guo, Z.; Chen, R.-M.; Wang, L. ; Wang, Y.; Ma, L.; Kumar, A.P. ; Zhu, T.; Wu, Z.-S.; Yin, Z.; Basappa; Goh, B.-C. ; Lobie, P.E. 
42018A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics studyWang, L ; Khoa Phan, D.-D; Syn, N; Xiang, X; Song, H; Thuya, W.L ; Yang, S ; Wong, A.L.-A ; Kumar, A.P ; Yong, W.P ; Sethi, G ; Ho, P.C.-L ; Goh, B.C 
52013An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteinsSubramaniam, A.; Loo, S.Y.; Rajendran, P.; Manu, K.A. ; Perumal, E.; Li, F.; Shanmugam, M.K. ; Siveen, K.S.; Park, J.-I.; Ahn, K.S.; Hui, K.M.; Kumar, A.P. ; Sethi, G.
62019An investigation on the therapeutic potential of butein, a tretrahydroxychalcone against human oral squamous cell carcinomaBordoloi, D.; Monisha, J.; Roy, N.K.; Padmavathi, G.; Banik, K.; Harsha, C.; Wang, H. ; Kumar, A.P. ; Arfuso, F.; Kunnumakkara, A.B.
72017Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironmentMoraes L.A. ; Kar S.; Foo S.L.; Gu T.; Toh Y.Q.; Ampomah P.B.; Sachaphibulkij K. ; Yap G. ; Zharkova O.; Lukman H.M. ; Fairhurst A.-M.; Kumar A.P. ; Lim L.H.K. 
83-Sep-2021Antibacterial and cellular behaviors of novel zinc-doped hydroxyapatite/graphene nanocomposite for bone tissue engineeringMaleki-Ghaleh, H.; Siadati, M. H.; Fallah, A.; Koc, B.; Kavanlouei, M.; Khademi-Azandehi, P.; Moradpur-Tari, E.; Omidi, Y.; Barar, J.; Beygi-Khosrowshahi, Y.; Kumar, Alan P. ; Adibkia, K.
91-Sep-2011Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathwayWoo, C.C.; Loo, S.Y.; Gee, V.; Yap, C.W. ; Sethi, G.; Kumar, A.P. ; Benny Tan, K.H.
102016ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferationYuan, Y ; Anbalagan, D; Lee, L.H; Samy, R.P ; Shanmugam, M.K ; Kumar, A.P ; Sethi, G ; Lobie, P.E ; Lim, L.H.K 
112017Art therapy and music reminiscence activity in the prevention of cognitive decline: Study protocol for a randomized controlled trialMahendran, R ; Rawtaer, I ; Fam, J ; Wong, J ; Kumar, A.P ; Gandhi, M ; Jing, K.X; Feng, L ; Kua, E.H 
122018Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: Findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual careMahendran R. ; Gandhi M. ; Moorakonda R.B. ; Wong J. ; Kanchi M.M. ; Fam J. ; Rawtaer I. ; Kumar A.P. ; Feng L. ; Kua E.H. 
132017Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4Bhuvanalakshmi, G; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India; Rangappa, K.S; Dharmarajan, A; Sethi, G ; Kumar, A.P ; Warrier, S
1415-Nov-2010Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cellsChua, A.W.L.; Hay, H.S. ; Rajendran, P.; Shanmugam, M.K. ; Li, F.; Bist, P.; Koay, E.S.C.; Lim, L.H.K.; Kumar, A.P. ; Sethi, G.
15Dec-2019c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progressionSim, Wen Jing ; Iyengar, Prasanna Vasudevan ; Lama, Dilraj; Lui, Sarah Kit Leng ; Ng, Hsien Chun ; Haviv-Shapira, Lior; Domany, Eytan; Kappei, Dennis ; Tan, Tuan Zea ; Saie, Azad; Jaynes, Patrick William ; Verma, Chandra Shekhar ; Kumar, Alan Prem ; Rouanne, Mathieu; Ha, Hong Koo; Radulescu, Camelia; ten Dijke, Peter; Eichhorn, Pieter Johan Adam ; Thiery, Jean Paul 
162018Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myelomaShanmugam, M.K ; Ahn, K.S; Lee, J.H; Kannaiyan, R; Mustafa, N ; Manu, K.A ; Siveen, K.S ; Sethi, G ; Chng, W.J ; Kumar, A.P 
17Nov-2011Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cellsKannaiyan, R.; Hay, H.S. ; Rajendran, P.; Li, F.; Shanmugam, M.K. ; Vali, S.; Abbasi, T.; Kapoor, S.; Sharma, A.; Kumar, A.P. ; Chng, W.-J.; Sethi, G.
18Oct-2011Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathwaysKannaiyan, R.; Manu, K.A. ; Chen, L.; Li, F.; Rajendran, P.; Subramaniam, A.; Lam, P.; Kumar, A.P. ; Sethi, G.
19Apr-2012Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In VivoRajendran, P.; Li, F.; Shanmugam, M.K. ; Kannaiyan, R.; Goh, J.; Wong, K. ; Wang, W.; Khin, E.; Tergaonkar, V.; Kumar, A. ; Luk, J.M.; Sethi, G.
2015-Dec-2020Cohort profile: the Diet and Healthy Aging (DaHA) study in SingaporeYu, Rongjun ; Sun, Ye; Ye, Kaisy Xinhong; Feng, Qiushi ; Lim, Su Lin; Mahendran, Rathi ; Cheah, Irwin Kee-Mun ; Foo, Roger Sik Yin ; Chua, Ru Yuan ; Gwee, Xinyi ; Loh, Marie; Sarmugam, Rani; Khine, Wei Wei Thwe ; Chao, Yin Xia; Larbi, Anis ; Lee, Yuan Kun ; Kumar, Alan Prem ; Kennedy, Brian K ; Kua, Ee Heok ; Feng, Lei