Browsing by Author Wu, Y.-T.

Showing results 1 to 9 of 9
Issue DateTitleAuthor(s)
2009Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagyWu, Y.-T.; Tan, H.-L.; Huang, Q. ; Ong, C.-N. ; Shen, H.-M. 
16-Jan-2013AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agentsZhou, J. ; Ng, S.; Huang, Q. ; Wu, Y.-T.; Li, Z.; Yao, S.Q. ; Shen, H.-M. 
2008Autophagy plays a protective role during zVAD-induced necrotic cell deathWu, Y.-T.; Tan, H.-L.; Huang, Q. ; Ong, C.-N.; Shen, H.-M.; Kim, Y.-S.; Liu, Z.-G.; Pan, N.; Ong, W.-Y.; Shen, H.-M.
2010Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinaseWu, Y.-T.; Tan, H.-L.; Huang, Q. ; Ong, C.-N. ; Shen, H.-M. ; Shui, G. ; Wenk, M.R. ; Bauvy, C.; Codogno, P.
2010Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinaseWu, Y.-T.; Tan, H.-L.; Huang, Q. ; Ong, C.-N. ; Shen, H.-M. ; Shui, G. ; Wenk, M.R. ; Bauvy, C.; Codogno, P.
Oct-2011Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stressNg, S.; Wu, Y.-T.; Chen, B. ; Zhou, J. ; Shen, H.-M. 
22-Apr-2011mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motifWu, Y.-T.; Ouyang, W.; Lazorchak, A.S.; Liu, D.; Shen, H.-M. ; Su, B.
Feb-2008Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell deathWu, Y.-T.; Zhang, S.; Kim, Y.-S.; Tan, H.-L.; Whiteman, M.; Ong, C.-N. ; Liu, Z.-G.; Ichijo, H.; Shen, H.-M. 
Jan-2011ZVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathwayWu, Y.-T.; Tan, H.-L.; Huang, Q. ; Sun, X.-J.; Zhu, X.; Shen, H.-M.