Browsing by Author Boelsterli, U.A.

Showing results 1 to 13 of 13
Issue DateTitleAuthor(s)
Oct-2006Bioactivation and hepatotoxicity of nitroaromatic drugsBoelsterli, U.A.; Ho, H.K.; Zhou, S. ; Leow, K.Y.
Aug-2006Drug acyl glucuronides: Reactivity and analytical implicationYang, X.-X.; Hu, Z.-P.; Boelsterli, U.A.; Zhou, S.-F. 
2013Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazoneLee, Y.H.; Goh, W.W.B.; Ng, C.K.; Raida, M.; Wong, L. ; Lin, Q. ; Boelsterli, U.A.; Chung, M.C.M.
Aug-2008Oxidative bioactivation and toxicity of leflunomide in immortalized human hepatocytes and kinetics of the non-enzymatic conversion to its major metabolite, A77 1726Seah, Q.M.; New, L.-S. ; Chan, E.C.Y. ; Boelsterli, U.A.
May-2006Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomideYang, X.-X.; Hu, Z.-P.; Chan, S.Y. ; Duan, W.; Ho, P.C.-L. ; Boelsterli, U.A.; Ng, K.-Y. ; Chan, E. ; Bian, J.-S.; Chen, Y.-Z. ; Huang, M.; Zhou, S.-F. 
2007Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometryNew, L.-S. ; Saha, S.; Ong, M.M.K.; Boelsterli, U.A.; Chan, E.C.Y. 
Feb-2008Proteomics profiling of hepatic mitochondria in heterozygous Sod2 +/- mice, an animal model of discreet mitochondrial oxidative stressYie, H.L.; Boelsterli, U.A.; Lin, Q. ; Chung, M.C.M.
15-Oct-2006St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosisHu, Z.-P.; Yang, X.-X.; Chan, S.Y. ; Xu, A.-L.; Duan, W.; Zhu, Y.-Z.; Sheu, F.-S. ; Boelsterli, U.A.; Chan, E. ; Zhang, Q.; Wang, J.-C.; Ee, P.L.R. ; Koh, H.L. ; Huang, M.; Zhou, S.-F. 
Feb-2008The mitochondrial superoxide/thioredoxin-2/ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytesLim, P.I.K.; Liu, J.; Go, M.I. ; Boelsterli, U.A.
Mar-2010The SOD2 mutant mouse as a model for oxidative stress: A functional proteomics perspectiveLee, Y.H.; Lin, Q. ; Boelsterli, U.A.; Chung, M.C.M.
Oct-2004Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4Zhou, S. ; Chan, E. ; Lim, L.Y. ; Boelsterli, U.A.; Li, S.C. ; Wang, J.; Zhang, Q.; Huang, M.; Xu, A.
15-Aug-2008Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- mice: Two-stage oxidative injuryLee, Y.H.; Chung, M.C.M.; Lin, Q. ; Boelsterli, U.A.
15-Jul-2009Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicityKashimshetty, R.; Desai, V.G.; Kale, V.M.; Lee, T.; Moland, C.L.; Branham, W.S.; New, L.S. ; Chan, E.C.Y. ; Younis, H.; Boelsterli, U.A.