Browsing by Author Sim Tiow Suan

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Issue DateTitleAuthor(s)
2003Deacetoxycephalosporin C synthase isozymes exhibit diverse catalytic activity and substrate specificityChin, H.S.; Sim, J.; Seah, K.I.; Sim, T.S. 
2005Differences in biochemical properties of the Plasmodial falcipain-2 and berghepain-2 orthologues: Implications for in vivo screens of inhibitorsChan, C.; Goh, L.L.; Sim, T.-S. 
2009Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin productionGoo, K.-S. ; Chua, C.-S.; Sim, T.-S. 
2008Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonolsChua, C.S.; Biermann, D.; Goo, K.S. ; Sim, T.-S. 
2005Endorsing functionality of Burkholderia pseudomallei glyoxylate cycle genes as anti-persistence drug screensLye, Y.M.; Chan, M. ; Sim, T.-S. 
2004Engineering recombinant Streptomyces coelicolor malate synthase with improved thermal properties by directed mutagenensisKoh, R. ; Goh, L.-L.; Sim, T.-S. 
2005Erratum: Differences in biochemical properties of the Plasmodial falcipain-2 and berghepain-2 orthologues: Implications for in vivo screens of inhibitors (FEMS Microbiology Letters (2005) 249 (315-321) DOI: 10.1016/j.femsle.2005.06.024)Chan, C.; Goh, L.L.; Sim, T.-S. 
1-Dec-1997Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, J.; Sim, T.-S. 
12-Jan-1996Functional analysis of conserved histidine residues in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesisTan, D.S.H. ; Sim, T.-S. 
2004Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from Plasmodium falciparumChan, M.; Sim, T.-S. 
Jan-2004Functional characterization of an alternative [lactate dehydrogenase-like] malate dehydrogenase in Plasmodium falciparumChan, M.; Sim, T.S. 
2004Functional characterization of an alternative [lactate dehydrogenase-like] malate dehydrogenase in Plasmodium falciparumChan, M.; Sim, T.S. 
15-Apr-1999Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
1999Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
1994Histidine-272 of isopenicillin N synthase of Cephalosporium acremonium, which is possibly involved in iron binding, is essential for its catalytic activityTiow-Suan, S. ; Tan, D.S.H. 
2004Homology modeling and mutagenesis analyses of Plasmodium falciparum falcipain 2A: Implications for rational drug designGoh, L.L.; Sim, T.S. 
15-Oct-2004Homology modeling and mutagenesis analyses of Plasmodium falciparum falcipain 2A: Implications for rational drug designGoh, L.L.; Sim, T.S. 
2001In vitro conversion of penicillin G and ampicillin by recombinant Streptomyces clavuligerus NRRL 3585 deacetoxycephalosporin C synthaseSim, J.; Sim, T.-S. 
5-Sep-2001In vitro conversion of penicillin G and ampicillin by recombinant Streptomyces clavuligerus NRRL 3585 deacetoxycephalosporin C synthaseSim, J. ; Sim, T.-S. 
1991Incorporation of microbiologically treated spent brewery grains into broiler rationsOh, J.C.S.; Chng, A.L.; Jesudason, R.B.; Sim, T.S.