Browsing by Author Lee Kian Leong

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Showing results 14 to 32 of 32 < previous 
Issue DateTitleAuthor(s)
Feb-2010Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous stateLanner, F.; Lee, K.L. ; Sohl, M.; Holmborn, K.; Yang, H.; Wilbertz, J.; Poellinger, L. ; Rossant, J.; Farnebo, F.
2018HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promotersSuzuki N.; Vojnovic N.; Lee K.-L. ; Yang H. ; Gradin K.; Poellinger L. 
2018Hypoxia Regulates MicroRNA Expression in the Human Carotid BodyMkrtchian S.; Lee K.L. ; K�hlin J.; Ebberyd A.; Poelllinger L. ; Fagerlund M.J.; Eriksson L.I.
2017Hypoxia regulates microRNA expression in the human carotid bodyMkrtchian S.; Lee K.L. ; Kåhlin J.; Ebberyd A.; Poellinger L. ; Fagerlund M.J.; Eriksson L.I.
1-May-2013Hypoxia-induced arterial differentiation requires adrenomedullin and notch signalingLanner, F.; Lee, K.L. ; Ortega, G.C.; Sohl, M.; Li, X.; Jin, S.; Hansson, E.M.; Claesson-Welsh, L.; Poellinger, L. ; Lendahl, U.; Farnebo, F.
2018Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cellsKitajima S. ; Lee K.L. ; Fujioka M.; Sun W. ; You J.; Chia G.S.; Wanibuchi H.; Tomita S.; Araki M.; Kato H. ; Poellinger L. 
2019Identification of drugs for leukaemia differentiation therapy by network pharmacologyEleni G Christodoulou ; Lin Ming Lee ; Kian Leong Lee ; Tsz Kan Fung; Eric So; Enrico Petretto ; S. Tiong Ong ; Owen JL Rackham 
2013Identification of penfluridol as potential treatment for pancreatic cancer cellsWenwen Chien ; Kian Leong Lee ; Qiaoyang Sun ; Peer Wuensche; Makoto Sudo ; Lorenz Poellinger ; Jeffrey W. Tyner; Henry Yang, H. ; Phillip Koeffler 
2017Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene ExpressionSun W. ; Kato H. ; Kitajima S. ; Lee K.L. ; Gradin K.; Okamoto T.; Poelllinger L. 
May-2010Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cellsMain, H.; Lee, K.L. ; Yang, H.; Haapa-Paananen, S.; Edgren, H.; Jin, S.; Sahlgren, C.; Kallioniemi, O.; Poellinger, L. ; Lim, B.; Lendahl, U.
10-Oct-2013Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβJin, S.; Mutvei, A.P.; Chivukula, I.V.; Andersson, E.R.; Ramsköld, D.; Sandberg, R.; Lee, K.L. ; Kronqvist, P.; Mamaeva, V.; Östling, P.; Mpindi, J.-P.; Kallioniemi, O.; Screpanti, I.; Poellinger, L. ; Sahlgren, C.; Lendahl, U.
2014Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibitionNg K.P. ; Manjeri A. ; Lee K.L. ; Huang W. ; Tan S.Y. ; Chuah C.T.H. ; Poellinger L. ; Ong S.T. 
1-Oct-2013PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cellsChien, W. ; Lee, K.L. ; Ding, L.W. ; Wuensche, P.; Kato, H.; Doan, N.B.; Poellinger, L. ; Said, J.W.; Koeffler, H.P.
2016S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fateTyrakis P.A.; Palazon A.; Macias D.; Lee K.L. ; Phan A.T.; Veliça P.; You J.; Chia G.S.; Sim J.; Doedens A.; Abelanet A.; Evans C.E.; Griffiths J.R.; Poellinger L. ; Goldrath A.W.; Johnson R.S.
2014Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cellsChien W. ; Ding L.-W. ; Sun Q.-Y. ; Torres-Fernandez L.A.; Tan S.Z.; Xiao J. ; Lim S.L. ; Garg M. ; Lee K.L. ; Kitajima S. ; Takao S. ; Leong W.Z. ; Sun H.; Tokatly I.; Poellinger L. ; Gery S.; Koeffler P.H. 
2018The arginase inhibitor N ? -hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional targetNg K.P. ; Manjeri A. ; Lee L.M. ; Chan Z.E. ; Tan C.Y.; Tan Q.D. ; Majeed A. ; Lee K.L. ; Chuah C. ; Suda T. ; Ong S.T. 
2014The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growthUeda J. ; Ho J.C. ; Lee K.L. ; Kitajima S. ; Yang H. ; Sun W. ; Fukuhara N. ; Zaiden N.; Chan S.L. ; Tachibana M.; Shinkai Y.; Kato H. ; Poellinger L. 
15-Nov-2013The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanismsKhalesi, E.; Nakamura, H.; Lee, K.L. ; Putra, A.C.; Fukazawa, T.; Kawahara, Y.; Makino, Y.; Poellinger, L. ; Yuge, L.; Tanimoto, K.
Dec-2012Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signalingHao, N.; Lee, K.L. ; Furness, S.G.B.; Bosdotter, C.; Poellinger, L. ; Whitelaw, M.L.