Browsing by Author BOELSTERLI,URS ALEX

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Issue DateTitleAuthor(s)
2006Bioactivation and hepatotoxicity of nitroaromatic drugsBoelsterli, U.A. ; Leow, K.Y.; Zhou, S. ; Ho, H.K. 
2006Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytesLim, M.S.; Lim, P.L.K.; Gupta, R.; Boelsterli, U.A. 
2006Drug acyl glucuronides: Reactivity and analytical implicationYang, X.-X.; Hu, Z.-P.; Boelsterli, U.A. ; Zhou, S.-F. 
2005Human multidrug resistance associated protein 4 confers resistance to camptothecinsTian, Q. ; Zhang, J.; Chan, E.; Sui, Y.C.; Boelsterli, U.A. ; Ho, P.C.-L.; Zhou, S. ; Tan, T.M.C.; Duan, W. ; Yang, H. ; Bian, J.-S. ; Zhu, Y.-Z.; Huang, M.; Xiong, W.; Li, X.
2005Human multidrug resistance associated protein 4 confers resistance to camptothecinsTian, Q.; Zhang, J.; Chan, E.; Sui, Y.C.; Boelsterli, U.A. ; Ho, P.C.-L. ; Zhou, S. ; Tan, T.M.C.; Duan, W. ; Yang, H. ; Bian, J.-S. ; Zhu, Y.-Z. ; Huang, M.; Xiong, W.; Li, X.
2007Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoidsBian, H.S. ; Ngo, S.Y.Y.; Tan, W. ; Wong, C.H.; Tan, T.M.C. ; Boelsterli, U.A. 
2006Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytesLatchoumycandane, C. ; Seah, Q.M.; Tan, R.C.H.; Boelsterli, U.A. ; Sattabongkot, J.; Beerheide, W.
2007Mitochondrial abnormalities-A link to idiosyncratic drug hepatotoxicity?Boelsterli, U.A. ; Lim, P.L.K.
2005Mitochondrial permeability transition as a source of superoxide anion induced by the nitroaromatic drug nimesulide in vitroTay, V.K.S.; Wang, A.S.; Leow, K.Y.; Ong, M.M.K.; Boelsterli, U.A. ; Wong, K.P.
2007Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injuryLatchoumycandane, C. ; Goh, C.W.; Ong, M.M.K.; Boelsterli, U.A. 
2007Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04Lim, P.L.K.; Latchoumycandane, C.; Khoo, Y.M.; Lee, H.S. ; Boelsterli, U.A. ; Tan, W. ; Tan, T.M.C. ; Mok, W.C.; Lim, S.G. ; Sattabongkot, J.; Beerheide, W.
2007Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04Lim, P.L.K.; Latchoumycandane, C. ; Khoo, Y.M.; Lee, H.S. ; Boelsterli, U.A. ; Tan, W. ; Tan, T.M.C.; Mok, W.C.; Lim, S.G. ; Sattabongkot, J.; Beerheide, W.
2006Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/-miceOng, M.M.K.; Wang, A.S.; Leow, K.Y.; Khoo, Y.M.; Boelsterli, U.A. 
2005Oltipraz-induced phase 2 enzyme response conserved in cells lacking mitochondrial DNAChua, Y.L.; Zhang, D.; Whiteman, M. ; Armstrong, J.S. ; Boelsterli, U. ; Moore, P.K. 
2005Oltipraz-induced phase 2 enzyme response conserved in cells lacking mitochondrial DNAChua, Y.L.; Zhang, D.; Whiteman, M. ; Armstrong, J.S. ; Boelsterli, U. ; Moore, P.K. 
2006Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomideYang, X.-X.; Hu, Z.-P.; Chan, S.Y. ; Ho, P.C.-L. ; Boelsterli, U.A. ; Ng, K.-Y. ; Chan, E.; Chen, Y.-Z. ; Zhou, S.-F. ; Duan, W. ; Bian, J.-S. ; Huang, M.
2006Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomideYang, X.-X.; Hu, Z.-P.; Chan, S.Y. ; Ho, P.C.-L. ; Boelsterli, U.A. ; Ng, K.-Y. ; Chan, E.; Chen, Y.-Z. ; Zhou, S.-F. ; Duan, W. ; Bian, J.-S. ; Huang, M.
2007Pharmacokinetic study of intraperitoneally administered troglitazone in mice using ultra-performance liquid chromatography/tandem mass spectrometryNew, L.-S. ; Saha, S.; Boelsterli, U.A. ; CHAN CHUN YONG,ERIC ; Ong, M.M.K.
2008Proteomics profiling of hepatic mitochondria in heterozygous Sod2+/-mice, an animal model of discreet mitochondrial oxidative stressYie, H.L.; Boelsterli, U.A. ; Lin, Q. ; Chung, M.C.M. 
2006St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosisHu, Z.-P.; Yang, X.-X.; Chan, S.Y. ; Boelsterli, U.A. ; Chan, E.; Ee, P.L.R. ; Koh, H.L. ; Zhou, S.-F. ; Xu, A.-L.; DUAN WEI ; Zhu, Y.-Z. ; Sheu, F.-S. ; Zhang, Q.; Wang, J.-C.; Huang, M.