Browsing by Author TAN BEE JEN

Showing results 1 to 19 of 19
Issue DateTitleAuthor(s)
2013A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activitiesBera, H.; Tan, B.J. ; Sun, L.; Dolzhenko, A.V. ; Chui, W.-K. ; Chiu, G.N.C. 
Nov-2011Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cellsTan, B.-J. ; Tan, B.-H.; Chiu, G.N.C. 
2011Functionalized carbon nanomaterials: Exploring the interactions with Caco-2 cells for potential oral drug deliveryCoyuco, J.C.; Liu, Y.; Tan, B.-J. ; Chiu, G.N.C. 
Mar-2012Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatinChaudhury, A.; Tan, B.J. ; Das, S.; Chiu, G.N.C. 
Oct-2009Lipid-based nanoparticulate systems for the delivery of anti-cancer drug cocktails: Implications on pharmacokinetics and drug toxicitiesChiu, G.N.C. ; Wong, M.-Y.; Ling, L.-U.; Shaikh, I.M.; Tan, K.-B.; Chaudhury, A.; Tan, B.-J. 
Jul-2010Liposomal M-V-05: Formulation development and activity testing of a novel dihydrofolate reductase inhibitor for breast cancer therapyTan, B.J. ; Quek, K.S.; Wong, M.-Y.; Chui, W.K. ; Chiu, G.N.C. 
2013Liposome co-encapsulation of synergistic combination of irinotecan and doxorubicin for the treatment of intraperitoneally grown ovarian tumor xenograftShaikh, I.M.; Tan, K.-B.; Chaudhury, A.; Liu, Y.; Tan, B.-J. ; Tan, B.M.J.; Chiu, G.N.C. 
2012Perorally active nanomicellar formulation of quercetin in the treatment of lung cancerTan, B.-J. ; Liu, Y.; Chang, K.-L.; Lim, B.K.W.; Chiu, G.N.C. 
May-2013Role of oxidative stress, endoplasmic reticulum stress and ERK activation in triptolide-induced apoptosisTan, B.-J. ; Chiu, G.N.C. 
May-2008Synthesis and biological activity of fluorinated 7-aryl-2-pyridyl-6,7-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-amines [1]Dolzhenko, A.V. ; Tan, B.J. ; Dolzhenko, A.V. ; Chiu, G.N.C. ; Chui, W.K. 
2015Synthesis and biological activity of fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-aminesDolzhenko Anna V.; Tan Bee Jen ; Chiu Ngar Chee Gigi ; Chui Wai Keung ; Dolzhenko Anton V.
1-Jul-2009Synthesis and hererocyclizations of 3,4-dihydroquinazolin-2-yl guanidine in the search of new anticancer agentsDolzhenko, A.V. ; Foo, M.C.; Tan, B.J. ; Dolzhenko, A.V. ; Chiu, G.N.C. ; Chui, W.K. 
15-Nov-2008The C-terminus of PRK2/PKNγ is required for optimal activation by RhoA in a GTP-dependent mannerLim, W.G.; Chen, X.; Liu, J.-p.; Tan, B.J. ; Zhou, S.; Smith, A.; Lees, N.; Hou, L.; Gu, F.; Yu, X.Y.; Du, Y.; Smith, D.; Verma, C.; Liu, K.; Duan, W.
13-Oct-2006The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase CαSui, S.Y.; Zhu, Y.; Smith, D.; Verma, C. ; Wee, G.L.; Bee, J.T. ; Qiu, T.L.; Nam, S.C.; Cai, M.; Zhu, Y.-N.; Zhou, S.-F. ; Tan, S.-L.; Duan, W.
13-Oct-2006The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase CαSui, S.Y.; Zhu, Y.; Smith, D.; Verma, C. ; Wee, G.L.; Bee, J.T. ; Qiu, T.L.; Nam, S.C.; Cai, M.; Zhu, Y.-N.; Zhou, S.-F. ; Tan, S.-L.; Duan, W.
1-Jun-2005The PKCα-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signalsZhu, Y.; Dong, Q.; Tan, B.J. ; Lim, W.G.; Zhou, S. ; Duan, W.
Sep-2006The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signalingLim, W.G.; Tan, B.J. ; Zhu, Y.; Zhou, S. ; Armstrong, J.S.; Li, Q.T.; Dong, Q.; Chan, E. ; Smith, D.; Verma, C.; Tan, S.-L.; Duan, W.
Jun-2006The very C-terminus of protein kinase Cε is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1 BZhu, Y.; Smith, D.; Verma, C. ; Lim, W.G.; Tan, B.J. ; Armstrong, J.S.; Zhou, S. ; Chan, E. ; Tan, S.-L.; Zhu, Y.-Z.; Cheung, N.S.; Duan, W.
2006The very C-terminus of protein kinase Cε is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1BZhu, Y. ; Lim, W.G.; Tan, B.J. ; Armstrong, J.S.; Cheung, N.S. ; Duan, W. ; Smith, D.; Verma, C. ; Zhou, S. ; Chan, E. ; Tan, S.-L.; Zhu, Y.-Z.