Browsing by Author ONG SIN TIONG

Showing results 1 to 11 of 11
Issue DateTitleAuthor(s)
2014A novel Bcr-Abl-mtor-eIF4a axis regulates IRES-mediated translation of LEF-1Tsai B.P.; Jimenez J.; Lim S. ; Fitzgerald K.D.; Zhang M.; Chuah C.T.H.; Axelrod H.; Nelson L.; Ong S.T. ; Semler B.L.; Waterman M.L.
19-Jun-2018BIM Deletion Polymorphism Profiling Complements Prognostic Values of Risk Scores in Imatinib-treated Asian Chronic Myeloid Leukemia PatientsHein Than; Weng Kit Lye ; Colin Sng; John Allen, S. ; Tiong Ong ; Charles Chuah 
Feb-2010Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitorJanes, M.R.; Limon, J.J.; So, L.; Chen, J.; Lim, R.J.; Chavez, M.A.; Vu, C.; Lilly, M.B.; Mallya, S.; Ong, S.T. ; Konopleva, M.; Martin, M.B.; Ren, P.; Liu, Y.; Rommel, C.; Fruman, D.A.
2014Identification of cis-acting elements and splicing factors involved in the regulation of BIM pre-mRNA splicingJuan W.C.; Roca X.; Ong S.T. 
2019Identification of drugs for leukaemia differentiation therapy by network pharmacologyEleni G Christodoulou ; Lin Ming Lee ; Kian Leong Lee ; Tsz Kan Fung; Eric So; Enrico Petretto ; S. Tiong Ong ; Owen JL Rackham 
Oct-2008Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistanceZhang, M.; Fu, W.; Prabhu, S.; Moore, J.C.; Ko, J.; Kim, J.W.; Druker, B.J.; Trapp, V.; Fruehauf, J.; Gram, H.; Fan, H.Y.; Ong, S.T. 
2014Multi-agent chemotherapy overcomes glucocorticoid resistance conferred by a BIM deletion polymorphism in pediatric acute lymphoblastic leukemiaSoh S.X.; Lim J.Y.S. ; Huang J.W.J.; Jiang N. ; Yeoh A.E.J. ; Ong S.T. 
2014Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibitionNg K.P. ; Manjeri A. ; Lee K.L. ; Huang W. ; Tan S.Y. ; Chuah C.T.H. ; Poellinger L. ; Ong S.T. 
2018The arginase inhibitor N ? -hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional targetNg K.P. ; Manjeri A. ; Lee L.M. ; Chan Z.E. ; Tan C.Y.; Tan Q.D. ; Majeed A. ; Lee K.L. ; Chuah C. ; Suda T. ; Ong S.T. 
2017The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemiaRauzan M. ; Chuah C.T.H. ; Ko T.K. ; Tiong Ong S. 
2012The role of protein phosphorylation in therapy resistance and disease progression in chronic myelogenous leukemiaJuan, W.C.; Ong, S.T.