Browsing by Author Steven George Rozen

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Issue DateTitleAuthor(s)
May-2012A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targetsDeng, N. ; Goh, L.K. ; Wang, H.; Das, K. ; Tao, J.; Tan, I.B.; Zhang, S.; Lee, M.; Wu, J.; Lim, K.H.; Lei, Z.; Goh, G.; Lim, Q.-Y.; Tan, A.L.-K.; Poh, D.Y.S.; Riahi, S.; Bell, S.; Shi, M.M.; Linnartz, R.; Zhu, F.; Yeoh, K.G.; Toh, H.C.; Yong, W.P. ; Cheong, H.C.; Rha, S.Y.; Boussioutas, A.; Grabsch, H.; Rozen, S. ; Tan, P. 
2013Alterations in metabolic pathways and networks in Alzheimer's diseaseKaddurah-Daouk, R.; Zhu, H.; Sharma, S.; Bogdanov, M.; Rozen, S.G. ; Matson, W.; Oki, N.O.; Motsinger-Reif, A.A.; Churchill, E.; Lei, Z.; Appleby, D.; Kling, M.A.; Trojanowski, J.Q.; Doraiswamy, P.M.; Arnold, S.E.
2009Alterations in tryptophan and purine metabolism in cocaine addiction: A metabolomic studyPatkar, A.A.; Rozen, S. ; Mannelli, P.; Matson, W.; Pae, C.-U.; Krishnan, K.R. ; Kaddurah-Daouk, R.
2011Assessing matched normal and tumor pairs in next-generation sequencing studiesGoh, L. ; Chen, G.B.; Cutcutache, I. ; Low, B.; Teh, B.T.; Rozen, S. ; Tan, P. 
2-Nov-2012AZFc deletions and spermatogenic failure: A population-based survey of 20,000 y chromosomesRozen, S.G. ; Marszalek, J.D.; Irenze, K.; Skaletsky, H.; Brown, L.G.; Oates, R.D.; Silber, S.J.; Ardlie, K.; Page, D.C.
Mar-2013CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United StatesLim, S.-H.; Tran-Viet, K.-N.; Yanovitch, T.L.; Freedman, S.F.; Klemm, T.; Call, W.; Powell, C.; Ravichandran, A.; Metlapally, R.; Nading, E.B.; Rozen, S. ; Young, T.L. 
20-Jul-2011Defending male fertilityRozen, S. 
Mar-2012Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokinesIvan, F.X.; Rajapakse, J.C.; Welsch, R.E.; Rozen, S.G. ; Narasaraju, T.; Xiong, G.M.; Engelward, B.P.; Chow, V.T.
2014Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genesYeo Z.X.; Wong J.C.L.; Rozen S.G. ; Lee A.S.G. 
Dec-2013Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancersChan-On, W.; Nairismägi, M.-L.; Ong, C.K.; Lim, W.K.; Dima, S.; Pairojkul, C.; Lim, K.H.; McPherson, J.R.; Cutcutache, I. ; Heng, H.L.; Ooi, L.; Chung, A.; Chow, P.; Cheow, P.C.; Lee, S.Y.; Choo, S.P.; Tan, I.B.H.; Duda, D.; Nastase, A.; Myint, S.S.; Wong, B.H.; Gan, A.; Rajasegaran, V.; Ng, C.C.Y.; Nagarajan, S.; Jusakul, A.; Zhang, S.; Vohra, P.; Yu, W.; Huang, D.; Sithithaworn, P.; Yongvanit, P.; Wongkham, S.; Khuntikeo, N.; Bhudhisawasdi, V.; Popescu, I.; Rozen, S.G. ; Tan, P. ; Teh, B.T.
2012Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genesZang, Z.J.; Cutcutache, I. ; Poon, S.L.; Zhang, S.L.; Mcpherson, J.R.; Tao, J.; Rajasegaran, V.; Heng, H.L.; Deng, N. ; Gan, A.; Lim, K.H.; Ong, C.K.; Huang, D.; Chin, S.Y. ; Tan, I.B.; Ng, C.C.Y.; Yu, W.; Wu, Y.; Lee, M.; Wu, J.; Poh, D.; Wan, W.K.; Rha, S.Y.; So, J.; Salto-Tellez, M. ; Yeoh, K.G.; Wong, W.K.; Zhu, Y.-J.; Futreal, P.A.; Pang, B.; Ruan, Y.; Hillmer, A.M.; Bertrand, D.; Nagarajan, N.; Rozen, S. ; Teh, B.T.; Tan, P. 
2012Exome sequencing of liver flukeg-associated cholangiocarcinomaOng, C.K.; Subimerb, C.; Pairojkul, C.; Wongkham, S.; Cutcutache, I. ; Yu, W.; McPherson, J.R.; Allen, G.E.; Ng, C.C.Y.; Wong, B.H.; Myint, S.S.; Rajasegaran, V.; Heng, H.L.; Gan, A.; Zang, Z.J.; Wu, Y.; Wu, J.; Lee, M.H.; Huang, D.; Ong, P.; Chan-On, W.; Cao, Y.; Qian, C.-N.; Lim, K.H.; Ooi, A.; Dykema, K.; Furge, K.; Kukongviriyapan, V.; Sripa, B.; Wongkham, C.; Yongvanit, P.; Futreal, P.A.; Bhudhisawasdi, V.; Rozen, S. ; Tan, P. ; Teh, B.T.
27-Aug-2013Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humansChua, E.C.-P.; Shui, G. ; Lee, I.T.G.; Lau, P.; Tan, L.-C.; Yeo, S.-C.; Lam, B.D.; Bulchand, S.; Summers, S.A.; Puvanendran, K.; Rozen, S.G. ; Wenk, M.R.; Gooley, J.J.
2011Fanconi's anemia in adulthood: Chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencingTan, I.B.; Cutcutache, I. ; Zang, Z.J.; Iqbal, J.; Yap, S.F.; Hwang, W.; Lim, W.-T.; Teh, B.T.; Rozen, S. ; Tan, E.-H.; Tan, P. 
2011First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneumYu W. ; Chan-On W.; Teo M. ; Ong C.K.; Cutcutache I. ; Allen G.E.; Wong B. ; Myint S.S.; Lim K.H.; Voorhoeve P.M. ; Rozen S. ; Soo K.C. ; Tan P. ; Teh B.T. 
2011Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencingZang, Z.J.; Ong, C.K.; Cutcutache, I. ; Yu, W.; Zhang, S.L.; Huang, D.; Ler, L.D.; Dykema, K.; Gan, A.; Tao, J.; Lim, S.; Liu, Y.; Futreal, P.A.; Grabsch, H.; Furge, K.A.; Goh, L.K. ; Rozen, S. ; Teh, B.T.; Tan, P. 
May-2010Genome-scale technologies foster advances in neurological and behavioral researchRozen, S. 
7-Aug-2013Genome-wide mutational signatures of aristolochic acid and its application as a screening toolPoon, S.L.; Pang, S.-T.; McPherson, J.R.; Yu, W.; Huang, K.K.; Guan, P.; Weng, W.-H.; Siew, E.Y.; Liu, Y.; Heng, H.L.; Chong, S.C.; Gan, A.; Tay, S.T.; Lim, W.K.; Cutcutache, I. ; Huang, D.; Ler, L.D.; Nairismägi, M.-L.; Lee, M.H.; Chang, Y.-H.; Yu, K.-J.; Chan-On, W.; Li, B.-K.; Yuan, Y.-F.; Qian, C.-N.; Ng, K.-F.; Wu, C.-F.; Hsu, C.-L.; Bunte, R.M. ; Stratton, M.R.; Andrew Futreal, P.; Sung, W.-K. ; Chuang, C.-K.; Ong, C.K.; Rozen, S.G. ; Tan, P. ; Teh, B.T.
Sep-2012Genomics and genetics of human and primate y chromosomesHughes, J.F.; Rozen, S. 
2015High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancerTan I.B. ; Malik S. ; Ramnarayanan K. ; McPherson J.R. ; Ho D.L.; Suzuki Y. ; Ng S.B.; Yan S.; Lim K.H.; Koh D.; Hoe C.M.; Chan C.Y.; Ten R.; Goh B.K.P.; Chung A.Y.F.; Tan J.; Chan C.X.; Tay S.T. ; Alexander L.; Nagarajan N.; Hillmer A.M.; Tang C.L.; Chua C.; Teh B.T. ; Rozen S. ; Tan P.