Browsing by Author CHIU NGAR CHEE,GIGI

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Issue DateTitleAuthor(s)
Sep-2007A cationic liposomal vincristine formulation with improved vincristine retention, extended circulation lifetime and increased anti-tumor activityWebb, M.S.; Boman, N.L.; Masin, D.; Yapp, D.; Ramsay, E.; Chiu, G.N.C. ; Cullis, P.R.; Bally, M.B.
2013A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activitiesBera, H.; Tan, B.J. ; Sun, L.; Dolzhenko, A.V. ; Chui, W.-K. ; Chiu, G.N.C. 
Feb-2009Development and characterization of a nanocarrier for quercetinWong, M.-Y.; Chiu, G.N.C. 
6-May-2014Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: Synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part IIBera, H.; Ojha, P.K.; Tan, B.J.; Sun, L.; Dolzhenko, A.V. ; Chui, W.-K. ; Chiu, G.N.C. 
9-Dec-2013Dual-functionalized PAMAM dendrimers with improved P-glycoprotein inhibition and tight junction modulating effectLiu, Y.; Chiu, G.N.C. 
Nov-2011Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cellsTan, B.-J. ; Tan, B.-H.; Chiu, G.N.C. 
2013Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1, 5-a][1,3,5]triazines as thymidine phosphorylase inhibitorsSun, L.; Li, J.; Bera, H.; Dolzhenko, A.V.; Chiu, G.N.C. ; Chui, W.K. 
2011Functionalized carbon nanomaterials: Exploring the interactions with Caco-2 cells for potential oral drug deliveryCoyuco, J.C.; Liu, Y.; Tan, B.-J. ; Chiu, G.N.C. 
10-Jun-2012In vivo efficacy of a novel liposomal formulation of safingol in the treatment of acute myeloid leukemiaTan, K.-B.; Ling, L.-U.; Bunte, R.M. ; Chng, W.-J.; Chiu, G.N.C. 
Mar-2012Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatinChaudhury, A.; Tan, B.J. ; Das, S.; Chiu, G.N.C. 
Oct-2012Intercellular cytosolic transfer correlates with mesenchymal stromal cell rescue of umbilical cord blood cell viability during ex vivo expansionChu, P.P.Y.; Bari, S.; Fan, X.; Gay, F.P.H.; Ang, J.M.L.; Chiu, G.N.C. ; Lim, S.K.; Hwang, W.Y.K.
Oct-2009Lipid-based nanoparticulate systems for the delivery of anti-cancer drug cocktails: Implications on pharmacokinetics and drug toxicitiesChiu, G.N.C. ; Wong, M.-Y.; Ling, L.-U.; Shaikh, I.M.; Tan, K.-B.; Chaudhury, A.; Tan, B.-J. 
Jul-2010Liposomal M-V-05: Formulation development and activity testing of a novel dihydrofolate reductase inhibitor for breast cancer therapyTan, B.J. ; Quek, K.S.; Wong, M.-Y.; Chui, W.K. ; Chiu, G.N.C. 
2013Liposome co-encapsulation of synergistic combination of irinotecan and doxorubicin for the treatment of intraperitoneally grown ovarian tumor xenograftShaikh, I.M.; Tan, K.-B.; Chaudhury, A.; Liu, Y.; Tan, B.-J. ; Tan, B.M.J.; Chiu, G.N.C. 
Dec-2011Liposome formulation of co-encapsulated vincristine and quercetin enhanced antitumor activity in a trastuzumab-insensitive breast tumor xenograft modelWong, M.-Y.; Chiu, G.N.C. 
1-Jul-2012Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibrationChaudhury, A.; Das, S.; Lee, R.F.S.; Tan, K.-B.; Ng, W.-K. ; Tan, R.B.H. ; Chiu, G.N.C. 
Mar-2007Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructsChiu, G.N.C. ; Edwards, L.A.; Kapanen, A.I.; Malinen, M.M.; Dragowska, W.H.; Warburton, C.; Chikh, G.G.; Fang, K.Y.Y.; Tan, S.; Sy, J.; Tucker, C.; Waterhouse, D.N.; Klasa, R.; Bally, M.B.
Dec-2006Optimization and therapeutic activity of liposome-conjugated monoclonal antibodies against the ErbB family of receptor tyrosine kinases: First step in the development of therapeutic antibody/liposomal anticancer drug combinationsChiu, G.N.C. ; Harasym, T.O.; Tardi, P.G.; Bally, M.B.; Waterhouse, D.N.
2012Perorally active nanomicellar formulation of quercetin in the treatment of lung cancerTan, B.-J. ; Liu, Y.; Chang, K.-L.; Lim, B.K.W.; Chiu, G.N.C. 
2012Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograftChaudhury, A.; Das, S.; Bunte, R.M. ; Chiu, G.N.C.