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ALAN PREM KUMAR
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Issue Date
Title
Author(s)
2017
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma
Dai X.
;
Wang L.
;
Deivasigamni A.
;
Looi C.Y.
;
Karthikeyan C.
;
Trivedi P.
;
Chinnathambi A.
;
Alharbi S.A.
;
Arfuso F.
;
Dharmarajan A.
;
Goh B.C.
;
Hui K.M.
;
Kumar A.P.
;
Mustafa M.R.
;
Sethi G.
2018
A review on liquid chromatography-tandem mass spectrometry methods for rapid quantification of oncology drugs
Wong, A.L.-A
;
Xiang, X
;
Ong, P.S
;
Mitchell, E.Q.Y
;
Syn, N
;
Wee, I
;
Kumar, A.P
;
Yong, W.P
;
Sethi, G
;
Goh, B.C
;
Ho, P.C.-L
;
Wang, L
2018
A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics study
Wang, L
;
Khoa Phan, D.-D
;
Syn, N
;
Xiang, X
;
Song, H
;
Thuya, W.L
;
Yang, S
;
Wong, A.L.-A
;
Kumar, A.P
;
Yong, W.P
;
Sethi, G
;
Ho, P.C.-L
;
Goh, B.C
2013
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins
Subramaniam, A.
;
Loo, S.Y.
;
Rajendran, P.
;
Manu, K.A.
;
Perumal, E.
;
Li, F.
;
Shanmugam, M.K.
;
Siveen, K.S.
;
Park, J.-I.
;
Ahn, K.S.
;
Hui, K.M.
;
Kumar, A.P.
;
Sethi, G.
2017
Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment
Moraes L.A.
;
Kar S.
;
Foo S.L.
;
Gu T.
;
Toh Y.Q.
;
Ampomah P.B.
;
Sachaphibulkij K.
;
Yap G.
;
Zharkova O.
;
Lukman H.M.
;
Fairhurst A.-M.
;
Kumar A.P.
;
Lim L.H.K.
1-Sep-2011
Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway
Woo, C.C.
;
Loo, S.Y.
;
Gee, V.
;
Yap, C.W.
;
Sethi, G.
;
Kumar, A.P.
;
Benny Tan, K.H.
2016
ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferation
Yuan, Y
;
Anbalagan, D
;
Lee, L.H
;
Samy, R.P
;
Shanmugam, M.K
;
Kumar, A.P
;
Sethi, G
;
Lobie, P.E
;
Lim, L.H.K
2017
Art therapy and music reminiscence activity in the prevention of cognitive decline: Study protocol for a randomized controlled trial
Mahendran, R
;
Rawtaer, I
;
Fam, J
;
Wong, J
;
Kumar, A.P
;
Gandhi, M
;
Jing, K.X
;
Feng, L
;
Kua, E.H
2018
Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: Findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual care
Mahendran R.
;
Gandhi M.
;
Moorakonda R.B.
;
Wong J.
;
Kanchi M.M.
;
Fam J.
;
Rawtaer I.
;
Kumar A.P.
;
Feng L.
;
Kua E.H.
2017
Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
Bhuvanalakshmi, G
;
Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India
;
Rangappa, K.S
;
Dharmarajan, A
;
Sethi, G
;
Kumar, A.P
;
Warrier, S
15-Nov-2010
Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells
Chua, A.W.L.
;
Hay, H.S.
;
Rajendran, P.
;
Shanmugam, M.K.
;
Li, F.
;
Bist, P.
;
Koay, E.S.C.
;
Lim, L.H.K.
;
Kumar, A.P.
;
Sethi, G.
Dec-2019
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
Sim, Wen Jing
;
Iyengar, Prasanna Vasudevan
;
Lama, Dilraj
;
Lui, Sarah Kit Leng
;
Ng, Hsien Chun
;
Haviv-Shapira, Lior
;
Domany, Eytan
;
Kappei, Dennis
;
Tan, Tuan Zea
;
Saie, Azad
;
Jaynes, Patrick William
;
Verma, Chandra Shekhar
;
Kumar, Alan Prem
;
Rouanne, Mathieu
;
Ha, Hong Koo
;
Radulescu, Camelia
;
ten Dijke, Peter
;
Eichhorn, Pieter Johan Adam
;
Thiery, Jean Paul
2018
Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myeloma
Shanmugam, M.K
;
Ahn, K.S
;
Lee, J.H
;
Kannaiyan, R
;
Mustafa, N
;
Manu, K.A
;
Siveen, K.S
;
Sethi, G
;
Chng, W.J
;
Kumar, A.P
Nov-2011
Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
Kannaiyan, R.
;
Hay, H.S.
;
Rajendran, P.
;
Li, F.
;
Shanmugam, M.K.
;
Vali, S.
;
Abbasi, T.
;
Kapoor, S.
;
Sharma, A.
;
Kumar, A.P.
;
Chng, W.-J.
;
Sethi, G.
Oct-2011
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways
Kannaiyan, R.
;
Manu, K.A.
;
Chen, L.
;
Li, F.
;
Rajendran, P.
;
Subramaniam, A.
;
Lam, P.
;
Kumar, A.P.
;
Sethi, G.
Apr-2012
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In Vivo
Rajendran, P.
;
Li, F.
;
Shanmugam, M.K.
;
Kannaiyan, R.
;
Goh, J.
;
Wong, K.
;
Wang, W.
;
Khin, E.
;
Tergaonkar, V.
;
Kumar, A.
;
Luk, J.M.
;
Sethi, G.
2009
Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human
Venkatachalam, G.
;
Clement, M.V.
;
Kumar, A.P.
;
Yue, L.S.
;
Pervaiz, S.
;
Sakharkar, M.K.
2009
Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human
Venkatachalam G.
;
Kumar A.P.
;
Yue L.S.
;
Pervaiz S.
;
Clement M.V.
;
Sakharkar M.K.
18-Jan-2019
Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective
Ong, Mei Shan
;
Deng, Shuo
;
Halim, Clarissa Esmeralda
;
Cai, Wanpei
;
Tan, Tuan Zea
;
Huang, Ruby Yun-Ju
;
Sethi, Gautam
;
Hooi, Shing Chuan
;
Kumar, Alan Prem
;
Yap, Celestial T
Apr-2013
Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: Evidence for non-canonical activation of RhoA and Rac1 GTPases
Zhu, Y.
;
Casey, P.J.
;
Kumar, A.P.
;
Pervaiz, S.