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Browsing by Author ALAN PREM KUMAR

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Issue DateTitleAuthor(s)
2017A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinomaDai X.; Wang L. ; Deivasigamni A.; Looi C.Y.; Karthikeyan C.; Trivedi P.; Chinnathambi A.; Alharbi S.A.; Arfuso F.; Dharmarajan A.; Goh B.C. ; Hui K.M. ; Kumar A.P. ; Mustafa M.R.; Sethi G. 
2018A review on liquid chromatography-tandem mass spectrometry methods for rapid quantification of oncology drugsWong, A.L.-A ; Xiang, X; Ong, P.S ; Mitchell, E.Q.Y; Syn, N; Wee, I; Kumar, A.P ; Yong, W.P ; Sethi, G ; Goh, B.C ; Ho, P.C.-L ; Wang, L 
2018A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics studyWang, L ; Khoa Phan, D.-D; Syn, N; Xiang, X; Song, H; Thuya, W.L ; Yang, S ; Wong, A.L.-A ; Kumar, A.P ; Yong, W.P ; Sethi, G ; Ho, P.C.-L ; Goh, B.C 
2013An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteinsSubramaniam, A.; Loo, S.Y.; Rajendran, P.; Manu, K.A. ; Perumal, E.; Li, F.; Shanmugam, M.K. ; Siveen, K.S.; Park, J.-I.; Ahn, K.S.; Hui, K.M.; Kumar, A.P. ; Sethi, G.
2017Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironmentMoraes L.A. ; Kar S.; Foo S.L.; Gu T.; Toh Y.Q.; Ampomah P.B.; Sachaphibulkij K. ; Yap G. ; Zharkova O.; Lukman H.M. ; Fairhurst A.-M.; Kumar A.P. ; Lim L.H.K. 
1-Sep-2011Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathwayWoo, C.C.; Loo, S.Y.; Gee, V.; Yap, C.W. ; Sethi, G.; Kumar, A.P. ; Benny Tan, K.H.
2016ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferationYuan, Y ; Anbalagan, D; Lee, L.H; Samy, R.P ; Shanmugam, M.K ; Kumar, A.P ; Sethi, G ; Lobie, P.E ; Lim, L.H.K 
2017Art therapy and music reminiscence activity in the prevention of cognitive decline: Study protocol for a randomized controlled trialMahendran, R ; Rawtaer, I ; Fam, J ; Wong, J ; Kumar, A.P ; Gandhi, M ; Jing, K.X; Feng, L ; Kua, E.H 
2018Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder: Findings from a pilot randomized controlled trial for art therapy and music reminiscence activity versus usual careMahendran R. ; Gandhi M. ; Moorakonda R.B. ; Wong J. ; Kanchi M.M. ; Fam J. ; Rawtaer I. ; Kumar A.P. ; Feng L. ; Kua E.H. 
2017Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4Bhuvanalakshmi, G; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India; Rangappa, K.S; Dharmarajan, A; Sethi, G ; Kumar, A.P ; Warrier, S
15-Nov-2010Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cellsChua, A.W.L.; Hay, H.S. ; Rajendran, P.; Shanmugam, M.K. ; Li, F.; Bist, P.; Koay, E.S.C.; Lim, L.H.K.; Kumar, A.P. ; Sethi, G.
Dec-2019c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progressionSim, Wen Jing ; Iyengar, Prasanna Vasudevan ; Lama, Dilraj; Lui, Sarah Kit Leng ; Ng, Hsien Chun ; Haviv-Shapira, Lior; Domany, Eytan; Kappei, Dennis ; Tan, Tuan Zea ; Saie, Azad; Jaynes, Patrick William ; Verma, Chandra Shekhar ; Kumar, Alan Prem ; Rouanne, Mathieu; Ha, Hong Koo; Radulescu, Camelia; ten Dijke, Peter; Eichhorn, Pieter Johan Adam ; Thiery, Jean Paul 
2018Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myelomaShanmugam, M.K ; Ahn, K.S; Lee, J.H; Kannaiyan, R; Mustafa, N ; Manu, K.A ; Siveen, K.S ; Sethi, G ; Chng, W.J ; Kumar, A.P 
Nov-2011Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cellsKannaiyan, R.; Hay, H.S. ; Rajendran, P.; Li, F.; Shanmugam, M.K. ; Vali, S.; Abbasi, T.; Kapoor, S.; Sharma, A.; Kumar, A.P. ; Chng, W.-J.; Sethi, G.
Oct-2011Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathwaysKannaiyan, R.; Manu, K.A. ; Chen, L.; Li, F.; Rajendran, P.; Subramaniam, A.; Lam, P.; Kumar, A.P. ; Sethi, G.
Apr-2012Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In VivoRajendran, P.; Li, F.; Shanmugam, M.K. ; Kannaiyan, R.; Goh, J.; Wong, K. ; Wang, W.; Khin, E.; Tergaonkar, V.; Kumar, A. ; Luk, J.M.; Sethi, G.
2009Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of humanVenkatachalam, G. ; Clement, M.V. ; Kumar, A.P. ; Yue, L.S.; Pervaiz, S. ; Sakharkar, M.K.
2009Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of humanVenkatachalam G.; Kumar A.P. ; Yue L.S. ; Pervaiz S. ; Clement M.V. ; Sakharkar M.K. 
18-Jan-2019Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic PerspectiveOng, Mei Shan; Deng, Shuo ; Halim, Clarissa Esmeralda ; Cai, Wanpei ; Tan, Tuan Zea ; Huang, Ruby Yun-Ju ; Sethi, Gautam ; Hooi, Shing Chuan ; Kumar, Alan Prem ; Yap, Celestial T 
Apr-2013Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: Evidence for non-canonical activation of RhoA and Rac1 GTPasesZhu, Y.; Casey, P.J. ; Kumar, A.P. ; Pervaiz, S.
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