Browsing by Author Lim Kah Leong

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Issue DateTitleAuthor(s)
Mar-2014A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cellsLu, H.F.; Chai, C. ; Lim, T.C.; Leong, M.F.; Lim, J.K.; Gao, S.; Lim, K.L. ; Wan, A.C.A.
2014A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease modelsLi L.; Zhang C.-W.; Chen G.Y. ; Zhu B. ; Chai C. ; Xu Q.-H. ; Tan E.-K. ; Zhu Q. ; Lim K.-L. ; Yao S.Q. 
2015A Small-Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson's DiseaseLi L. ; Zhang C.-W.; Ge J. ; Qian L. ; Chai B.-H.; Zhu Q.; Lee J.-S.; Lim K.-L. ; Yao S.Q. 
May-2013AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's diseaseHaskin, J.; Szargel, R.; Shani, V.; Mekies, L.N.; Rott, R.; Lim, G.G.Y.; Lim, K.-L. ; Bandopadhyay, R.; Wolosker, H.; Engelender, S.
2017AF-6 protects against dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson’s diseaseBasil A.H.; Sim J.P.L.; Lim G.G.Y.; Lin S.; Chan H.Y.; Engelender S.; Lim K.-L. 
Apr-2005Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutationsWang, C.; Tan, J.M.M.; Ho, M.W.L.; Zaiden, N.; Siew, H.W. ; Chew, C.L.C.; Pei, W.E.; Tit, M.L. ; Dawson, T.M.; Kah, L.L. 
10-Oct-2012AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's diseaseNg, C.-H.; Guan, M.S.H.; Koh, C.; Ouyang, X.; Yu, F.; Tan, E.-K.; O'Neill, S.P.; Zhang, X.; Chung, J.; Lim, K.-L. 
2012Animal models of parkinsons disease 2012Imai, Y.; Venderova, K.; Lim, K.-L. 
2016Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2Angeles D.C. ; Ho P.; Dymock B.W. ; Lim K.-L. ; Zhou Z.-D.; Tan E.-K. 
2018APP upregulation contributes to retinal ganglion cell degeneration via JNK3Liu C. ; Zhang C.-W.; Zhou Y. ; Wong W.Q.; Lee L.C. ; Ong W.Y. ; Yoon S.O.; Hong W.; Fu X.-Y. ; Soong T.W. ; Koo E.H. ; Stanton L.W.; Lim K.-L. ; Xiao Z.-C.; Dawe G.S. 
Aug-2008Autophagy-mediated clearance of aggresomes is not a universal phenomenonWong, E.S.P.; Tan, J.M.M.; Soong, W.-E.; Hussein, K.; Nukina, N.; Dawson, V.I.; Dawson, T.M.; Cuervo, A.M.; Lim, K.-L. 
2000Calmodulin binds to and inhibits the activity of the membrane distal catalytic domain of receptor protein-tyrosine phosphatase ?Liang L.; Lim K.L. ; Seow K.T.; Ng C.H.; Pallen C.J. 
1999Catalytic activation of the membrane distal domain of protein tyrosine phosphatase ?, but not CD45, by two point mutationsLim K.L. ; Ng C.H. ; Pallen C.J. 
2015Convergence of parkin, PINK1, and α-synuclein on stress-induced mitochondrial morphological remodelingNorris, K.L.; Hao, R.; Chen, L.-F.; Lai, C.-H.; Kapur, M.; Shaughnessy, P.J.; Chou, D.; Yan, J.; Taylor, J.P.; Engelender, S.; West, A.E.; Lim Kah Leong ; Yao, T.-P.
2018Correction to: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy (Cell Research, (2018), 10.1038/s41422-018-0056-0)Wang L. ; Cho Y.-L. ; Tang Y.; Wang J. ; Park J.-E.; Wu Y. ; Wang C.; Tong Y. ; Chawla R. ; Zhang J. ; Shi Y. ; Deng S. ; Lu G.; Wu Y.; Tan H.W.-S. ; Pawijit P.; Lim G.G.-Y.; Chan H.-Y.; Zhang J.; Fang L.; Yu H. ; Liou Y.-C.; Karthik M. ; Bay B.-H. ; Lim K.-L. ; Sze S.-K.; Yap C.T. ; Shen H.-M. 
2015Cytosolic PTEN-induced putative kinase 1 Is stabilized by the NF- ? B pathway and promotes non-selective mitophagyLim G.G.Y.; Chua D.S.K.; Basil A.H.; Chan H.-Y.; Chai C.; Arumugam T. ; Lim K.-L. 
2015DAMPs and neurodegenerationThundyil J.; Lim K.-L. 
2008Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasivenessDe La Iglesia N.; Konopka G.; Lim K.-L. ; Nutt C.L.; Bromberg J.F.; Frank D.A.; Mischel P.S.; Louis D.N.; Bonni A.
2005Differential expression of splice variant and wild-type parkin in sporadic Parkinson's diseaseTan E.K. ; Shen H. ; Tan J.M.M.; Lim K.L. ; Fook-Chong S. ; Hu W.P.; Paterson M.C. ; Chandran V.R.; Yew K.; Tan C. ; Yuen Y. ; Pavanni R. ; Wong M.C. ; Puvan K.; Zhao Y.
2005Differential expression of splice variant and wild-type parkin in sporadic Parkinson's diseaseTan E.K. ; Shen H.; Tan J.M.M. ; Lim K.L. ; Fook-Chong S. ; Hu W.P.; Paterson M.C. ; Chandran V.R.; Yew K.; Tan C.; Yuen Y. ; Pavanni R. ; Wong M.C. ; Puvan K. ; Zhao Y.