Please use this identifier to cite or link to this item:
|Title:||Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells|
mesenchymal stem cells
|Source:||Nayak, T.R., Andersen, H., Makam, V.S., Khaw, C., Bae, S., Xu, X., Ee, P.-L.R., Ahn, J.-H., Hong, B.H., Pastorin, G., Özyilmaz, B. (2011-06-28). Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells. ACS Nano 5 (6) : 4670-4678. ScholarBank@NUS Repository. https://doi.org/10.1021/nn200500h|
|Abstract:||Current tissue engineering approaches combine different scaffold materials with living cells to provide biological substitutes that can repair and eventually improve tissue functions. Both natural and synthetic materials have been fabricated for transplantation of stem cells and their specific differentiation into muscles, bones, and cartilages. One of the key objectives for bone regeneration therapy to be successful is to direct stem cells proliferation and to accelerate their differentiation in a controlled manner through the use of growth factors and osteogenic inducers. Here we show that graphene provides a promising biocompatible scaffold that does not hamper the proliferation of human mesenchymal stem cells (hMSCs) and accelerates their specific differentiation into bone cells. The differentiation rate is comparable to the one achieved with common growth factors, demonstrating graphenes potential for stem cell research. © 2011 American Chemical Society.|
|Source Title:||ACS Nano|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 13, 2018
WEB OF SCIENCETM
checked on Jan 10, 2018
checked on Feb 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.