Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/94657
Title: Reaction of anionic oxygen donors with the antitumour copper(II)-pyridine-2-carbaldehyde thiosemicarbazone (HL) system and the crystal structure of [{Cu(HL)(H2PO4)}2][H2PO 4]2·2H3PO4·2H 2O
Authors: Ainscough, E.W.
Brodie, A.M.
Ranford, J.D. 
Waters, J.M.
Issue Date: 7-Apr-1997
Source: Ainscough, E.W.,Brodie, A.M.,Ranford, J.D.,Waters, J.M. (1997-04-07). Reaction of anionic oxygen donors with the antitumour copper(II)-pyridine-2-carbaldehyde thiosemicarbazone (HL) system and the crystal structure of [{Cu(HL)(H2PO4)}2][H2PO 4]2·2H3PO4·2H 2O. Journal of the Chemical Society - Dalton Transactions (7) : 1251-1255. ScholarBank@NUS Repository.
Abstract: The complexes [(CuL)2(XO4)]·nH2O (HL = pyridine-2-carbaldehyde thiosemicarbazone, X = HP, n = 6; X = Mo, n = 1), [{CuL(ptp)}2]·4H2O (Hptp = p-tritylphenol) and [{CuL(tip)}2] (Htip = 2,4,6-triiodophenol) have been prepared from the reaction of aqueous solutions of [{CuL(CH3CO2)}2] with salts of the appropriate oxygen donor. Also prepared were [{Cu(HL)(H2PO4)}2][H2PO 4]2·xH3PO4·nH 2O (x = 0, n = 3; x = 2, n = 2) from the reaction of [{CuL(CH3CO2)}2] with 2 mol dm-3 H1PO4 and phosphate species (arising from the hydrolysis of 2 mol dm-3 HPF6) respectively. The complexes have been characterized by a range of physicochemical techniques and the crystal and molecular structure of [{Cu(HL)(H2PO4)}2][H2PO 4]2·2H3PO4·2H 2O determined by single-crystal X-ray diffraction. The complex cation is a centrosymmetric dimer, the monomeric units having one-atom bridges from two H2PO4 - anions. The copper atom has a distorted square-pyramidal geometry with three donor atoms (NNS) from the neutral, tridentate HL ligand and the fourth in-plane donor (an oxygen) from the bridging anion. The fifth position is occupied by a less strongly bound oxygen from the second bridging anion. An extensive hydrogen-bonding scheme involving the bridging H2PO4 - anions, non-co-ordinated H2PO4 - anions, H3PO4 moieties, water molecules and ligand exists with one very strong contact of 2.436 Å. These complexes may serve as simple models for the interaction of this antitumour system with oxygen donors.
Source Title: Journal of the Chemical Society - Dalton Transactions
URI: http://scholarbank.nus.edu.sg/handle/10635/94657
ISSN: 03009246
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

24
checked on Jan 21, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.