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|Title:||Molecular sieve mediated decarboxylative Mannich and aldol reactions of β-ketoacids|
|Citation:||Zhong, F., Jiang, C., Yao, W., Xu, L.-W., Lu, Y. (2013-08-07). Molecular sieve mediated decarboxylative Mannich and aldol reactions of β-ketoacids. Tetrahedron Letters 54 (32) : 4333-4336. ScholarBank@NUS Repository.|
|Abstract:||A molecular sieve mediated decarboxylative Mannich reaction of β-ketoacids with sulfonyl imines is reported; this protocol leads to an efficient preparation of synthetically useful β-amino ketones. An analogous molecular sieve promoted decarboxylative aldol reaction between β-ketoacids and isatins is also described, which affords bioactive 3-substituted-3-hydroxy-oxindoles in excellent yields. © 2013 Elsevier Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
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