Please use this identifier to cite or link to this item: https://doi.org/10.1021/ja2100774
Title: Intracellular glutathione detection using MnO 2-nanosheet- modified upconversion nanoparticles
Authors: Deng, R.
Xie, X.
Vendrell, M.
Chang, Y.-T. 
Liu, X. 
Issue Date: 21-Dec-2011
Citation: Deng, R., Xie, X., Vendrell, M., Chang, Y.-T., Liu, X. (2011-12-21). Intracellular glutathione detection using MnO 2-nanosheet- modified upconversion nanoparticles. Journal of the American Chemical Society 133 (50) : 20168-20171. ScholarBank@NUS Repository. https://doi.org/10.1021/ja2100774
Abstract: We report a novel design, based on a combination of lanthanide-doped upconversion nanoparticles and manganese dioxide nanosheets, for rapid, selective detection of glutathione in aqueous solutions and living cells. In this approach, manganese dioxide (MnO 2) nanosheets formed on the surface of nanoparticles serve as an efficient quencher for upconverted luminescence. The luminescence can be turned on by introducing glutathione that reduces MnO 2 into Mn 2+. The ability to monitor the glutathione concentration intracellularly may enable rational design of a convenient platform for targeted drug and gene delivery. © 2011 American Chemical Society.
Source Title: Journal of the American Chemical Society
URI: http://scholarbank.nus.edu.sg/handle/10635/94083
ISSN: 00027863
DOI: 10.1021/ja2100774
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

383
checked on Jul 13, 2018

WEB OF SCIENCETM
Citations

371
checked on Jun 12, 2018

Page view(s)

30
checked on Jul 6, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.