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https://doi.org/10.1016/j.tetlet.2011.08.044
Title: | Hydroethidine as a probe for measuring superoxide formation rates during air oxidation of myricetin and quercetin | Authors: | Quek, Y.L. Huang, D. |
Keywords: | Fluorescent probe Hydroethidine Myricetin Pro-oxidant Superoxide |
Issue Date: | 12-Oct-2011 | Citation: | Quek, Y.L., Huang, D. (2011-10-12). Hydroethidine as a probe for measuring superoxide formation rates during air oxidation of myricetin and quercetin. Tetrahedron Letters 52 (41) : 5384-5387. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2011.08.044 | Abstract: | In the presence of the flavonols myricetin and quercetin, oxidation of hydroethidine (HE) by superoxide yielded ethidium (E+) instead of 2-hydroxyethidium (2-OH-E+). As a known pro-oxidant, myricetin alone was also found to be able to catalyze air oxidation of HE yielding exclusively E+. The reaction is inhibited by added superoxide dismutase, suggesting that superoxide is involved in the rate limiting step of the oxidation. © 2011 Elsevier Ltd. All rights reserved. | Source Title: | Tetrahedron Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/93976 | ISSN: | 00404039 | DOI: | 10.1016/j.tetlet.2011.08.044 |
Appears in Collections: | Staff Publications |
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