Please use this identifier to cite or link to this item:
|Title:||High-throughput discovery of mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry|
|Authors:||Tan, L.P. |
|Citation:||Tan, L.P., Wu, H., Yang, P.-Y., Kalesh, K.A., Zhang, X., Hu, M., Srinivasan, R., Yao, S.Q. (2009). High-throughput discovery of mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry. Organic Letters 11 (22) : 5102-5105. ScholarBank@NUS Repository. https://doi.org/10.1021/ol9023419|
|Abstract:||A ∼500-member library of bidentate inhibitors against protein tyrosine phosphatases (PTPs) was rapidly assembled using click chemistry. Subsequent high-throughput screening had led to the discovery of highly potent (K i as low as 150 nM) and selective MptpB inhibitors, some of which represent the most potent MptpB inhibitors developed to date. © 2009 American Chemical society.|
|Source Title:||Organic Letters|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 13, 2018
WEB OF SCIENCETM
checked on Jun 11, 2018
checked on Jun 29, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.