Please use this identifier to cite or link to this item:
|Title:||Complexes of platinum(II) or palladium(II) with 1,10-phenanthroline and amino acids|
|Keywords:||Amino acid complexes|
|Citation:||Jin, V.X., Ranford, J.D. (2000-06-15). Complexes of platinum(II) or palladium(II) with 1,10-phenanthroline and amino acids. Inorganica Chimica Acta 304 (1) : 38-44. ScholarBank@NUS Repository. https://doi.org/10.1016/S0020-1693(00)00061-X|
|Abstract:||The amino acids complexes of [Pt(phen)(AA)]NO3·xH2O and [Pd(phen)(AA)]NO3·xH2O have been prepared by the interaction of palladium and platinum complexes, [Pt(phen)Cl2] and [Pd(phen)Cl2] with salts of amino acids in methanol and characterized by 1H NMR and IR spectroscopy which confirmed the formation of a very large variety of compounds with ligand in a simple way (bidentate). All of these new compounds have been isolated and tested for cytotoxicity on Molt-4, a human leukaemia cell line. The IC50 values of [Pt(phen)(Pro)]Cl·2H2O and [Pd(phen)(Asp)]Cl·1.5H2O are 9.8 and 7.31 μM, respectively, exhibiting a significant activity which is close to cis-[PtCl2(NH3)2]. (C) 2000 Elsevier Science S.A.|
|Source Title:||Inorganica Chimica Acta|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Aug 15, 2018
WEB OF SCIENCETM
checked on Jul 23, 2018
checked on Aug 17, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.