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|Title:||A highly enantioselective synthesis of functionalized 2,3-dihydrofurans by a modified Feist-Bénary reaction|
|Citation:||Dou, X., Zhong, F., Lu, Y. (2012-10-29). A highly enantioselective synthesis of functionalized 2,3-dihydrofurans by a modified Feist-Bénary reaction. Chemistry - A European Journal 18 (44) : 13945-13948. ScholarBank@NUS Repository. https://doi.org/10.1002/chem.201202504|
|Abstract:||Organocatalysis: A modified Feist-Bénary reaction employing acyclic β-ketoesters as the dinucleophile and (E)-β,β-bromo nitrostyrenes as the dielectrophile was developed for the asymmetric synthesis of 2,3-dihydrofurans. L-Threonine-derived tertiary amine/thiourea catalysts were found to be the most efficient catalysts, inducing the reaction in a highly enantioselective manner (see scheme; TBDPS=tert-butyldiphenylsilyl). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.|
|Source Title:||Chemistry - A European Journal|
|Appears in Collections:||Staff Publications|
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