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https://doi.org/10.1039/b718304f
| Title: | "click" synthesis of small-molecule inhibitors targeting caspases | Authors: | Ng, S.L. Yang, P.-Y. Chen, K.Y.-T. Srinivasan, R. Yao, S.Q. |
Issue Date: | 2008 | Citation: | Ng, S.L., Yang, P.-Y., Chen, K.Y.-T., Srinivasan, R., Yao, S.Q. (2008). "click" synthesis of small-molecule inhibitors targeting caspases. Organic and Biomolecular Chemistry 6 (5) : 844-847. ScholarBank@NUS Repository. https://doi.org/10.1039/b718304f | Abstract: | A panel of 198 P4-diversified aldehyde (reversible) and vinyl sulfone (irreversible) inhibitors is successfully synthesized via an efficient "click chemistry" platform and directly screened against caspase-3 and -7 for inhibition. © The Royal Society of Chemistry. | Source Title: | Organic and Biomolecular Chemistry | URI: | http://scholarbank.nus.edu.sg/handle/10635/92865 | ISSN: | 14770520 | DOI: | 10.1039/b718304f |
| Appears in Collections: | Staff Publications |
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