Please use this identifier to cite or link to this item:
|Title:||Kinetic and equilibrium study of the enantioseparation of Fenoprofen in a batch setup|
|Authors:||Ching, C.B. |
|Source:||Ching, C.B.,Arlt, W.,Lisso, M.,Wozny, G. (2000-11). Kinetic and equilibrium study of the enantioseparation of Fenoprofen in a batch setup. Industrial and Engineering Chemistry Research 39 (11) : 4365-4369. ScholarBank@NUS Repository.|
|Abstract:||The bed voidage, axial dispersion, and kinetic and isotherm parameters for the chromatographic enantioseparation of racemic Fenoprofen, using cellulose ester as the chiral stationary phase and 2-propanol/hexane/acetyl alcohol as the mobile phase, were evaluated by moment analyses on the basis of equilibrium theory and the linear driving force model. The peak-fitting method was used to identify the coefficients of the competitive Langmuir isotherm for both enantiomers. For this reason and for the validation of the model parameters, a simulation program was developed. The simulated results describe the experimental data well. On the basis of the isotherm parameters and the equilibrium theory, the process region for the simulated moving bed (SMB) process was identified. Changes of the process region will be discussed by considering fluctuations in the feed concentration and uncertainties in the determined capacity factor.|
|Source Title:||Industrial and Engineering Chemistry Research|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 17, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.