Please use this identifier to cite or link to this item: https://doi.org/10.1021/je0499465
Title: Solubility of aspirin in supercritical carbon dioxide with and without Acetone
Authors: Huang, Z.
Lu, W.D.
Kawi, S. 
Chiew, Y.C.
Issue Date: Sep-2004
Source: Huang, Z., Lu, W.D., Kawi, S., Chiew, Y.C. (2004-09). Solubility of aspirin in supercritical carbon dioxide with and without Acetone. Journal of Chemical and Engineering Data 49 (5) : 1323-1327. ScholarBank@NUS Repository. https://doi.org/10.1021/je0499465
Abstract: The equilibrium solubility of aspirin in supercritical CO 2 has been determined using a dynamic method. Measurements were performed at pressures ranging from (10 to 25) MPa and temperatures from (308.15 to 328.15) K. The effect of a polar cosolvent, acetone, on the solubility of aspirin in supercritical carbon dioxide was also studied. The results show that the addition of acetone produces up to a 5-fold increase in the aspirin solubility. The solubility of aspirin in CO 2 is well described by the Peng-Robinson equation of state and density based correlations over the pressure and temperature ranges studied.
Source Title: Journal of Chemical and Engineering Data
URI: http://scholarbank.nus.edu.sg/handle/10635/90177
ISSN: 00219568
DOI: 10.1021/je0499465
Appears in Collections:Staff Publications

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