Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/89972
Title: Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye
Authors: Oh, S.K.W.
Chua, P.
Foon, K.L.
Ng, E.
Chin, A.
Choo, A.B.H.
Srinivasan, R. 
Keywords: Human embryonic stem cells
Identification
Stem cells
Teratoma
Issue Date: May-2009
Citation: Oh, S.K.W., Chua, P., Foon, K.L., Ng, E., Chin, A., Choo, A.B.H., Srinivasan, R. (2009-05). Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye. Biotechnology Letters 31 (5) : 653-658. ScholarBank@NUS Repository.
Abstract: An automated vision system, TeratomEye, was developed for the identification of three representative tissue types: muscle, gut and neural epithelia which are commonly found in teratomas formed from human embryonic stem cells. Muscle tissue, a common structure was identified with an accuracy of 90.3% with high specificity and sensitivity greater than 90%. Gut epithelia were identified with an accuracy of 87.5% with specificity and sensitivity greater than 80%. Neural epithelia which were the most difficult structures to distinguish gave an accuracy of 47.6%. TeratomEye is therefore useful for the automated identification of differentiated tissues in teratoma sections.
Source Title: Biotechnology Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/89972
ISSN: 01415492
Appears in Collections:Staff Publications

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