Please use this identifier to cite or link to this item:
|Title:||Polypyrrole nanospheres with magnetic and cell-targeting capabilities|
|Authors:||Wuang, S.C. |
|Source:||Wuang, S.C., Neoh, K.G., Kang, E.-T., Pack, D.W., Leckband, D.E. (2007-04-02). Polypyrrole nanospheres with magnetic and cell-targeting capabilities. Macromolecular Rapid Communications 28 (7) : 816-821. ScholarBank@NUS Repository. https://doi.org/10.1002/marc.200600873|
|Abstract:||The preparation of polypyrrole/Fe3O4 nanospheres by a facile mini-emulsion polymerization method is investigated using poly(ethylene glycol), poly(ethylene oxide), poly(vinyl alcohol), and hyaluronic acid as surfactants. Hyaluronic acid is deemed the most suitable surfactant since it results in well-dispersed nanospheres of 80-100 nm, and offers the advantages of biocompatibility, cell adhesive property, and the availability of functional groups for attachment of other molecules. These polypyrrole/Fe3O 4 nanospheres are magnetic and can be further functionalized with a cancer antibody, herceptin. Our results show that this combination of hyaluronic acid and herceptin results in high specific uptake of the nanospheres by cancer cells. © 2007 WILEY-VCH Verlag GmbH & Co. KGaA.|
|Source Title:||Macromolecular Rapid Communications|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 27, 2018
WEB OF SCIENCETM
checked on Feb 19, 2018
checked on Mar 12, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.