Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/89847
Title: Polymer microspheres with permanent antibacterial surface from surface-initiated atom transfer radical polymerization
Authors: Cheng, Z.
Zhu, X.
Shi, Z.L. 
Neoh, K.G. 
Kang, E.T. 
Issue Date: 31-Aug-2005
Citation: Cheng, Z., Zhu, X., Shi, Z.L., Neoh, K.G., Kang, E.T. (2005-08-31). Polymer microspheres with permanent antibacterial surface from surface-initiated atom transfer radical polymerization. Industrial and Engineering Chemistry Research 44 (18) : 7098-7104. ScholarBank@NUS Repository.
Abstract: Cross-linked poly(4-vinylbenzyl chloride) (PVBC) microspheres were first synthesized by suspension copolymerization of 4-vinylbenzyl chloride (VBC) in the presence of a cross-linking agent, ethylene glycol dimethacrylate (EGDMA). Subsequent modification of the microsphere surfaces via surface-initiated atom transfer radical polymerization (ATRP) of 2-(dimethylamino)ethyl methacrylate (DMAEMA), using the VBC units of PVBC on the microsphere surface as the macroinitiators, gave rise to well-defined (nearly monodisperse) and covalently tethered poly[2-(dimethylamino)ethyl methacrylate] (PDMAEMA) brushes. Quaternization of the tertiary amine groups of the PDMAEMA brushes with alkyl bromides (1-bromododecane or 1-bromohexane) gave rise to a high concentration of quaternary ammonium salt (QAS) on the microsphere surfaces. The chemical composition of the microsphere surfaces at various stages of surface modification was characterized by X-ray photoelectron spectroscopy (XPS). The bactericidal effect of the QAS-functionalized microspheres on Escherichia coli and Staphylococcus aureus was demonstrated. The permanence of the bactericidal activity was also demonstrated through the repeated applications of the surface-modified PVBC microspheres without any significant loss of their surface activity or functionality. © 2005 American Chemical Society.
Source Title: Industrial and Engineering Chemistry Research
URI: http://scholarbank.nus.edu.sg/handle/10635/89847
ISSN: 08885885
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

106
checked on Feb 27, 2018

WEB OF SCIENCETM
Citations

103
checked on Apr 23, 2018

Page view(s)

22
checked on May 4, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.