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|Title:||pH-Controllable drug release using hydrogel encapsulated mesoporous silica|
|Citation:||Song, S.-W., Hidajat, K., Kawi, S. (2007). pH-Controllable drug release using hydrogel encapsulated mesoporous silica. Chemical Communications (42) : 4396-4398. ScholarBank@NUS Repository.|
|Abstract:||Amine-functionalized mesoporous SBA-15 silica loaded with bovine serum albumin (BSA) has been successfully encapsulated with a thin layer coating of poly(acrylic acid) PAA, with the entrapped BSA being released from the PAA-encapsulated SBA-15 at the higher pH value of 7.4 rather than at the lower pH value of 1.2. This novel drug delivery system has a potential application in the release of protein drug to the site of higher pH value, such as small intestine or colon. © The Royal Society of Chemistry.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
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