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|Title:||Oligopeptide-modified silicon nanowire arrays as multichannel metal ion sensors|
|Authors:||Bi, X. |
|Keywords:||Metal ion sensor|
|Source:||Bi, X., Agarwal, A., Yang, K.-L. (2009-07-15). Oligopeptide-modified silicon nanowire arrays as multichannel metal ion sensors. Biosensors and Bioelectronics 24 (11) : 3248-3251. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bios.2009.04.007|
|Abstract:||Semiconducting nanowires have the potential to function as highly sensitive and selective sensors for label-free detection of biological and chemical species. In this paper, we describe the preparation and applications of oligopeptide-modified single crystal silicon nanowire (SiNW) arrays as multichannel metal ion sensors. Because these SiNW arrays were fabricated by using a "top-down" process, a very high density of individually addressable SiNW (180 SiNWs grouped into 36 clusters) can be manufactured on a single chip. Furthermore, after two different SiNW clusters are modified with Pb2+-selective and Cu2+-selective oligopeptide, respectively, concentrations of Pb2+ and Cu2+ in aqueous solutions can be detected simultaneously and selectively in two different channels. By using the SiNW arrays, we successfully achieved a detection limit of 1 nM for Pb2+ and 10 nM for Cu2+, respectively. These results demonstrate the potential utility of oligopeptide-modified SiNW arrays for highly sensitive and selective chemical and biological sensing applications. © 2009 Elsevier B.V. All rights reserved.|
|Source Title:||Biosensors and Bioelectronics|
|Appears in Collections:||Staff Publications|
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