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|Title:||Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution|
|Citation:||Tang, W.L., Li, Z., Zhao, H. (2010-08-14). Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution. Chemical Communications 46 (30) : 5461-5463. ScholarBank@NUS Repository. https://doi.org/10.1039/c0cc00735h|
|Abstract:||We report the first example of directed evolution of a P450 monooxygenase with inverted enantioselectivity for asymmetric biohydroxylation. The biohydroxylation product of the best mutant 1AF4A has an ee of 83% (R) compared to the wild type's ee of 43% (S). © The Royal Society of Chemistry 2010.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
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