Please use this identifier to cite or link to this item: https://doi.org/10.1039/c0cc00735h
Title: Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution
Authors: Tang, W.L.
Li, Z. 
Zhao, H.
Issue Date: 14-Aug-2010
Source: Tang, W.L., Li, Z., Zhao, H. (2010-08-14). Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution. Chemical Communications 46 (30) : 5461-5463. ScholarBank@NUS Repository. https://doi.org/10.1039/c0cc00735h
Abstract: We report the first example of directed evolution of a P450 monooxygenase with inverted enantioselectivity for asymmetric biohydroxylation. The biohydroxylation product of the best mutant 1AF4A has an ee of 83% (R) compared to the wild type's ee of 43% (S). © The Royal Society of Chemistry 2010.
Source Title: Chemical Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/89278
ISSN: 13597345
DOI: 10.1039/c0cc00735h
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