Please use this identifier to cite or link to this item:
|Title:||Direct comparison of α- And γ-glycine growth rates in acidic and basic solutions: New insights into glycine polymorphism|
|Citation:||Han, G., Chow, P.S., Tan, R.B.H. (2012-05-02). Direct comparison of α- And γ-glycine growth rates in acidic and basic solutions: New insights into glycine polymorphism. Crystal Growth and Design 12 (5) : 2213-2220. ScholarBank@NUS Repository. https://doi.org/10.1021/cg201321f|
|Abstract:||The growth rates of α- and γ-glycine in basic and acidic aqueous glycine solutions were investigated systematically using in situ microscopic observations on single crystal seeds. The most unexpected observation was that inorganic bases (e.g., NaOH and KOH) and acids (e.g., H 2SO 4) can significantly accelerate the growth of the metastable α-glycine. This finding is contrary to the recently postulated self-poisoning mechanism, which highlights that glycine ions, generated in a basic or acidic solution, inhibit α-glycine so as to permit γ-glycine to appear. Furthermore, it was observed that, in basic solutions, γ-glycine growth remains dominated by α-glycine growth, yet γ-glycine is crystallized preferentially. This strongly implies that the relative nucleation rates, not the relative growth kinetics of the two glycine polymorphs play a dominant role in determining the polymorphic outcome, providing new insights into the riddle of glycine polymorphism. The observed effects of the base and acid additives on the face growth rates of α-glycine and γ-glycine were rationalized at the molecular level. © 2012 American Chemical Society.|
|Source Title:||Crystal Growth and Design|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 17, 2018
WEB OF SCIENCETM
checked on Jun 27, 2018
checked on Apr 20, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.