Please use this identifier to cite or link to this item: https://doi.org/10.1021/ac400273g
Title: Development of an oligopeptide functionalized surface plasmon resonance biosensor for online detection of glyphosate
Authors: Ding, X.
Yang, K.-L. 
Issue Date: 18-Jun-2013
Source: Ding, X., Yang, K.-L. (2013-06-18). Development of an oligopeptide functionalized surface plasmon resonance biosensor for online detection of glyphosate. Analytical Chemistry 85 (12) : 5727-5733. ScholarBank@NUS Repository. https://doi.org/10.1021/ac400273g
Abstract: We report a surface plasmon resonance (SPR) biosensor for online detection of glyphosate. The surface of the sensing element is decorated with an oligopeptide, TPFDLRPSSDTR, which is identified by using phage display library. This oligopeptide shows high binding specificity for glyphosate (KD = 8.6 μM), probably because of the presence of R and D in the oligopeptide. To detect glyphosate in buffer solution, an SPR gold sensor chip is modified by using the oligopeptide with a surface density of 0.6 1/nm2. The sensitivity of this oligopeptide-functionalized SPR biosensor is 1.02 RU/μM whereas the limit of detection (LOD) is 0.58 μM. This oligopeptide functionalized SPR biosensor also shows good specificity against other analytes such as glycine, thiacloprid, and imidacloprid. © 2013 American Chemical Society.
Source Title: Analytical Chemistry
URI: http://scholarbank.nus.edu.sg/handle/10635/88757
ISSN: 00032700
DOI: 10.1021/ac400273g
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

14
checked on Mar 7, 2018

WEB OF SCIENCETM
Citations

13
checked on Mar 7, 2018

Page view(s)

33
checked on Apr 20, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.