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Title: Deposition method for preparing SERS-Active gold nanoparticle substrates
Authors: Kho, K.W.
Shen, Z.X. 
Zeng, H.C. 
Soo, K.C.
Olivo, M.
Issue Date: 15-Nov-2005
Citation: Kho, K.W., Shen, Z.X., Zeng, H.C., Soo, K.C., Olivo, M. (2005-11-15). Deposition method for preparing SERS-Active gold nanoparticle substrates. Analytical Chemistry 77 (22) : 7462-7471. ScholarBank@NUS Repository.
Abstract: Surface-enhanced Raman scattering or SERS, discovered some 20 years ago, has recently become a promising tool for routine biofluid assays in a clinical setting. Many attempts have been made to produce cheap and reproducible SERS-active substrates. In this study, we report on the fabrication of SERS-active substrates through the convective assembly of gold (Au) particles on electrostatically charged glass slides. We show that, by a proper control of the initial particle concentration in an evaporating Au suspension droplet, it is possible to obtain a closely packed colloidal film capable of generating SERS activity. Finally, AFM and SERS measurements of the resulting films reveal comparability in performance with previous silane-immobilized Au colloidal films. The minimum electromagnetic enhancement factor of our films is estimated to be about 2 × 104. © 2005 American Chemical Society.
Source Title: Analytical Chemistry
ISSN: 00032700
DOI: 10.1021/ac050437v
Appears in Collections:Staff Publications

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