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|Title:||Amplified fluorescence turn-on assay for mercury(II) detection and quantification based on conjugated polymer and silica nanoparticles|
|Citation:||Wang, Y., Liu, B. (2009-04-01). Amplified fluorescence turn-on assay for mercury(II) detection and quantification based on conjugated polymer and silica nanoparticles. Macromolecular Rapid Communications 30 (7) : 498-503. ScholarBank@NUS Repository. https://doi.org/10.1002/marc.200800727|
|Abstract:||An amplified fluorescence turn-on assay for mercury(II) detection and quantification was developed. This method makes use of specific thymine/mercury(II)/thymine coordination to capture F1-iabeled DMA onto MP surface. Addition of a cationic conjugated polymer leads to an amplified F1 signal in solution. A sigmoidal Hg2+ working curve is obtained at fixed [NP] with a detection limit of 0.1 × 10-6 m. However, by reducing [Hg2+] and [NP] simultaneously, while maintaining [Hg 2+]:[DNA duplex] = 3:1, a linear calibration curve is observed with a detection limit of 5 × 10-9 m. The CCP-assisted mercury(II) assay shows potential applications in environmental mercury detection and for industrial process control. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA.|
|Source Title:||Macromolecular Rapid Communications|
|Appears in Collections:||Staff Publications|
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