Please use this identifier to cite or link to this item:
|Title:||Clickable poly(ester amine) dendrimer-grafted Fe3O4 nanoparticles prepared via successive Michael addition and alkyne-azide click chemistry|
|Citation:||Li, M., Xu, L.Q., Wang, L., Wu, Y.P., Li, J., Neoh, K.-G., Kang, E.-T. (2011-06). Clickable poly(ester amine) dendrimer-grafted Fe3O4 nanoparticles prepared via successive Michael addition and alkyne-azide click chemistry. Polymer Chemistry 2 (6) : 1312-1321. ScholarBank@NUS Repository. https://doi.org/10.1039/c1py00084e|
|Abstract:||Nanospheres, consisting of a Fe3O4 core, a silica inner shell and dendritic poly(ester amine) (PEA) outer shell, were synthesized via the sol-gel reaction, and successive Michael addition and alkyne-azide click chemistry. The resultant PEA dendrimer-grafted magnetic nanoparticles (Fe 3O4-g-PEA) were characterized by X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FT-IR) spectroscopy, and thermogravimetric (TGA) analysis. Transmission electron microscopy (TEM) images reveal that the Fe3O4-g-PEA magnetic nanoparticles (MNPs) have a uniform size distribution of about 30 nm in diameter. The hydrodynamic size of Fe3O4-g-PEA MNPs changes reversibly with pH of the aqueous medium in the pH range of 3 to 9. The clickable alkyne groups on the surface of Fe3O4-g-PEA MNPs endow these nanoparticles with a functionalizable surface via alkyne-azide click chemistry. Assays with 3T3 fibroblasts and RAW macrophage cells indicate that the Fe3O 4-g-PEA MNPs possess very low cytotoxicity. Hence, the PEA dendrimer-grafted magnetic nanospheres have potential applications as biomedical materials. © 2011 The Royal Society of Chemistry.|
|Source Title:||Polymer Chemistry|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 13, 2018
WEB OF SCIENCETM
checked on Jun 12, 2018
checked on Jul 20, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.