Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00216-006-0552-9
Title: Miniaturized platforms for the detection of single-nucleotide polymorphisms
Authors: Ng, J.K.-K.
Liu, W.-T. 
Keywords: Hybridization
Microarrays
Microfluidics
Miniaturization
Single-nucleotide polymorphisms (SNPs)
Issue Date: Oct-2006
Source: Ng, J.K.-K., Liu, W.-T. (2006-10). Miniaturized platforms for the detection of single-nucleotide polymorphisms. Analytical and Bioanalytical Chemistry 386 (3) : 427-434. ScholarBank@NUS Repository. https://doi.org/10.1007/s00216-006-0552-9
Abstract: Conventional methods for detecting single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in human beings, are mostly limited by their analysis time and throughputs. In contrast, advances in microfabrication technology have led to the development of miniaturized platforms that can potentially provide rapid high-throughput analysis at small sample volumes. This review highlights some of the recent developments in the miniaturization of SNP detection platforms, including microarray-based, bead-based microfluidic and microelectrophoresis-based platforms. Particular attention is paid to their ease of fabrication, analysis time, and level of throughput. © Springer-Verlag 2006.
Source Title: Analytical and Bioanalytical Chemistry
URI: http://scholarbank.nus.edu.sg/handle/10635/87558
ISSN: 16182642
DOI: 10.1007/s00216-006-0552-9
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

32
checked on Mar 27, 2018

WEB OF SCIENCETM
Citations

29
checked on Mar 27, 2018

Page view(s)

24
checked on Apr 20, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.