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|Title:||Synthesis, characterization and preliminary toxicity assays of NIR-active Au-silicate nanoparticles through a sol-gel processing|
|Source:||Ren, L., Zhang, Q.-Q., Chow, G.-M. (2006-09). Synthesis, characterization and preliminary toxicity assays of NIR-active Au-silicate nanoparticles through a sol-gel processing. Journal of Sol-Gel Science and Technology 39 (3) : 269-274. ScholarBank@NUS Repository. https://doi.org/10.1007/s10971-006-8158-4|
|Abstract:||Monodisperse Au-silicate nanoparticles (10.7±1.6 nm in diameter) were prepared by reduction of aqueous solution containing 2 mM HAuCl4 with sodium citrate (1 wt.%) in a hydrosol, in which small clusters of silicate formed by hydrolysis and polymerization of 3-aminopropyltrimethoxysilane (APTMS). APTMS covalently linked to reduced gold particles through its -NH 2 end-group. UV-vis spectra of the obtained Au-silicate nanoparticles showed a peak at ∼ 690 nm due to the interface effects between the Au and the silicate matrix. The Au-silicate nanoparticles exhibited near-IR (NIR) sensitivity. Cytotoxicity and limited hemocompatibility in vitro for the prepared Au-silicate nanoparticles were also investigated. It was shown that at lower concentration (|
|Source Title:||Journal of Sol-Gel Science and Technology|
|Appears in Collections:||Staff Publications|
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