Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10971-006-8158-4
Title: Synthesis, characterization and preliminary toxicity assays of NIR-active Au-silicate nanoparticles through a sol-gel processing
Authors: Ren, L.
Zhang, Q.-Q.
Chow, G.-M. 
Keywords: Biomaterials
Nano-hybrids
Optical properties
Sol-gel growth
Toxicity
Issue Date: Sep-2006
Citation: Ren, L., Zhang, Q.-Q., Chow, G.-M. (2006-09). Synthesis, characterization and preliminary toxicity assays of NIR-active Au-silicate nanoparticles through a sol-gel processing. Journal of Sol-Gel Science and Technology 39 (3) : 269-274. ScholarBank@NUS Repository. https://doi.org/10.1007/s10971-006-8158-4
Abstract: Monodisperse Au-silicate nanoparticles (10.7±1.6 nm in diameter) were prepared by reduction of aqueous solution containing 2 mM HAuCl4 with sodium citrate (1 wt.%) in a hydrosol, in which small clusters of silicate formed by hydrolysis and polymerization of 3-aminopropyltrimethoxysilane (APTMS). APTMS covalently linked to reduced gold particles through its -NH 2 end-group. UV-vis spectra of the obtained Au-silicate nanoparticles showed a peak at ∼ 690 nm due to the interface effects between the Au and the silicate matrix. The Au-silicate nanoparticles exhibited near-IR (NIR) sensitivity. Cytotoxicity and limited hemocompatibility in vitro for the prepared Au-silicate nanoparticles were also investigated. It was shown that at lower concentration (
Source Title: Journal of Sol-Gel Science and Technology
URI: http://scholarbank.nus.edu.sg/handle/10635/86773
ISSN: 09280707
DOI: 10.1007/s10971-006-8158-4
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