Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.colsurfb.2013.08.031
Title: Effects of plasma treatment to nanofibers on initial cell adhesion and cell morphology
Authors: Liu, W.
Zhan, J.
Su, Y.
Wu, T.
Wu, C.
Ramakrishna, S. 
Mo, X.
Al-Deyab, S.S.
El-Newehy, M.
Keywords: Electrospinning
Hydrophilicity
Initial cell adhesion
Nanofibrous mat
Plasma treatment
Issue Date: 1-Jan-2014
Citation: Liu, W., Zhan, J., Su, Y., Wu, T., Wu, C., Ramakrishna, S., Mo, X., Al-Deyab, S.S., El-Newehy, M. (2014-01-01). Effects of plasma treatment to nanofibers on initial cell adhesion and cell morphology. Colloids and Surfaces B: Biointerfaces 113 : 101-106. ScholarBank@NUS Repository. https://doi.org/10.1016/j.colsurfb.2013.08.031
Abstract: Poly-l-lactic acid (PLLA) nanofibers were fabricated by electrospinning and treated with O2 plasma. The surface properties of PLLA nanofibers before and after plasma treatment were characterized by water contact angle measurement and X-ray photoelectron spectroscopy (XPS). It was found that the hydrophilicity of PLLA nanofibers was improved and the amount of oxygen-containing groups increased after plasma treatment. Initial cell adhesion was evaluated by cell capture efficiency based on the cell count method. The results showed that initial porcine mesenchymal stem cells (pMSCs) adhesion to plasma-treated nanofibers was significantly enhanced. Moreover, the morphology of pMSCs on PLLA nanofibers (PLLA NFS) and plasma-treated PLLA nanofibers (P-PLLA NFS) were observed by scanning electron microscope (SEM) after 10min, 20min, 30min and 60min cell adhesion. It was found that plasma treatment to electrospun nanofibers had a great effect on pMSCs morphology at earlier time points. Therefore, plasma treatment is an efficient surface modification strategy to improve cell adhesion in earlier culture time intervals. It may be a promising method in the design of novel tissue-engineered scaffolds. © 2013 Elsevier B.V.
Source Title: Colloids and Surfaces B: Biointerfaces
URI: http://scholarbank.nus.edu.sg/handle/10635/85082
ISSN: 09277765
DOI: 10.1016/j.colsurfb.2013.08.031
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

35
checked on Dec 12, 2018

WEB OF SCIENCETM
Citations

31
checked on Dec 12, 2018

Page view(s)

47
checked on Dec 7, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.