Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.3689751
Title: Physical limits of pure superparamagnetic Fe 3O 4 nanoparticles for a local hyperthermia agent in nanomedicine
Authors: Jeun, M.
Lee, S. 
Kyeong Kang, J.
Tomitaka, A.
Wook Kang, K.
Il Kim, Y.
Takemura, Y.
Chung, K.-W.
Kwak, J.
Bae, S. 
Issue Date: 27-Feb-2012
Citation: Jeun, M., Lee, S., Kyeong Kang, J., Tomitaka, A., Wook Kang, K., Il Kim, Y., Takemura, Y., Chung, K.-W., Kwak, J., Bae, S. (2012-02-27). Physical limits of pure superparamagnetic Fe 3O 4 nanoparticles for a local hyperthermia agent in nanomedicine. Applied Physics Letters 100 (9) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3689751
Abstract: Magnetic and AC magnetically induced heating characteristics of Fe 3O 4 nanoparticles (IONs) with different mean diameters, d, systematically controlled from 4.2 to 22.5 nm were investigated to explore the physical relationship between magnetic phase and specific loss power (SLP) for hyperthermia agent applications. It was experimentally confirmed that the IONs had three magnetic phases and correspondingly different SLP characteristics depending on the particle sizes. Furthermore, it was demonstrated that pure superparamagnetic phase IONs (d < 9.8 nm) showed insufficient SLPs critically limiting for hyperthermia applications due to smaller AC hysteresis loss power (Néel relaxation loss power) originated from lower out-of-phase magnetic susceptibility. © 2012 American Institute of Physics.
Source Title: Applied Physics Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/82907
ISSN: 00036951
DOI: 10.1063/1.3689751
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