Please use this identifier to cite or link to this item: https://doi.org/10.1166/jnn.2013.7524
Title: Physical contribution of néel and brown relaxation to interpreting intracellular hyperthermia characteristics using superparamagnetic nanofluids
Authors: Jeun, M.
Kim, Y.J.
Park, K.H.
Paek, S.H.
Bae, S. 
Keywords: Brown Relaxation Loss Power
Intracellular Hyperthermia
Néel Relaxation Loss Power
Superparamagnetic Nanofluid
Issue Date: Aug-2013
Citation: Jeun, M., Kim, Y.J., Park, K.H., Paek, S.H., Bae, S. (2013-08). Physical contribution of néel and brown relaxation to interpreting intracellular hyperthermia characteristics using superparamagnetic nanofluids. Journal of Nanoscience and Nanotechnology 13 (8) : 5719-5725. ScholarBank@NUS Repository. https://doi.org/10.1166/jnn.2013.7524
Abstract: In this work, the AC magnetically-induced heating characteristics of various viscous nanofluids with either soft ferrite (Fe3O2) or hard ferrite (CoFe2O2) superparamagnetic nanoparticles (SPNPs) were investigated to empirically and physically interpret the contribution of "Néel relaxation loss power, PNéel relaxation loss," or "Brown relaxation loss power, PBrownrelaxation loss," to the total AC heat generation of intracellular hyperthermia or in-vivo hyperthermia. It was found that the contribution of PBrownrelaxation loss to the total AC heating power, Ptotal, and the specific loss power (SLP) was severely affected by the surrounding environment (or in-vivo environment) while the contribution of PNéel relaxation loss to the Ptotal was independent of the variation of surrounding environment. Furthermore, all the theoretical and experimental results strongly suggested that highly efficacious intracellular hyperthermia (or in-vivo hyperthermia) modality can be achieved by enhancing the PNéel relaxation loss rather than the PBrownrelaxation loss of SPNP agents in nanofluids. Copyright © 2013 American Scientific Publishers All rights reserved.
Source Title: Journal of Nanoscience and Nanotechnology
URI: http://scholarbank.nus.edu.sg/handle/10635/82906
ISSN: 15334880
DOI: 10.1166/jnn.2013.7524
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