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|Title:||Microsphere-coupled scanning laser confocal nanoscope for sub-diffraction-limited imaging at 25 nm lateral resolution in the visible spectrum|
scanning laser confocal microscope
|Source:||Yan, Y., Li, L., Feng, C., Guo, W., Lee, S., Hong, M. (2014-02-25). Microsphere-coupled scanning laser confocal nanoscope for sub-diffraction-limited imaging at 25 nm lateral resolution in the visible spectrum. ACS Nano 8 (2) : 1809-1816. ScholarBank@NUS Repository. https://doi.org/10.1021/nn406201q|
|Abstract:||We report a direct optical super-resolution imaging approach with 25 nm (∼λ/17) lateral resolution under 408 nm wavelength illumination by combining fused silica and polystyrene microspheres with a conventional scanning laser confocal microscope (SLCM). The microsphere deposited on the target surface generates a nanoscale central lobe illuminating a sub-diffraction- limited cross-section located on the target surface. The SLCM confocal pinhole isolates the reflected light from the near-field subdiffractive cross-section and suppresses the noises from the side lobe and the far-field paraxial focal point. The structural detail of the subdiffractive cross-section is therefore captured, and the 2D target surface near the bottom of microspheres can be imaged by intensity-based point scanning. © 2014 American Chemical Society.|
|Source Title:||ACS Nano|
|Appears in Collections:||Staff Publications|
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