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|Title:||High sensitivity molecule detection by plasmonic nanoantennas with selective binding at electromagnetic hotspots|
|Citation:||Zhang, N., Liu, Y.J., Yang, J., Su, X., Deng, J., Chum, C.C., Hong, M., Teng, J. (2014-02-07). High sensitivity molecule detection by plasmonic nanoantennas with selective binding at electromagnetic hotspots. Nanoscale 6 (3) : 1416-1422. ScholarBank@NUS Repository. https://doi.org/10.1039/c3nr04494g|
|Abstract:||We report a highly sensitive biomolecule detection by plasmonic nanoantenna arrays with selective binding at the optical hotspots. The plasmonic nanoantennas consist of two separated Au nanorods with a thin Ti disk placed in between. By using selective surface modification chemistry, controlled binding occurs only in the gaps between the plasmonic nanoantennas, which ensures a high detection sensitivity. Both optical characterization using a dark field microscope and the FDTD simulation show that after the streptavidin binding, the signal increases with decreasing gap size. Compared to a single nanorod, the signal obtained per bound molecule in the nanoantennas increases by a factor of six, which is promising with respect to the future detection of single molecules. © 2013 The Royal Society of Chemistry.|
|Appears in Collections:||Staff Publications|
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