Please use this identifier to cite or link to this item: https://doi.org/10.1039/c3nr04494g
Title: High sensitivity molecule detection by plasmonic nanoantennas with selective binding at electromagnetic hotspots
Authors: Zhang, N.
Liu, Y.J.
Yang, J.
Su, X.
Deng, J.
Chum, C.C.
Hong, M. 
Teng, J.
Issue Date: 7-Feb-2014
Citation: Zhang, N., Liu, Y.J., Yang, J., Su, X., Deng, J., Chum, C.C., Hong, M., Teng, J. (2014-02-07). High sensitivity molecule detection by plasmonic nanoantennas with selective binding at electromagnetic hotspots. Nanoscale 6 (3) : 1416-1422. ScholarBank@NUS Repository. https://doi.org/10.1039/c3nr04494g
Abstract: We report a highly sensitive biomolecule detection by plasmonic nanoantenna arrays with selective binding at the optical hotspots. The plasmonic nanoantennas consist of two separated Au nanorods with a thin Ti disk placed in between. By using selective surface modification chemistry, controlled binding occurs only in the gaps between the plasmonic nanoantennas, which ensures a high detection sensitivity. Both optical characterization using a dark field microscope and the FDTD simulation show that after the streptavidin binding, the signal increases with decreasing gap size. Compared to a single nanorod, the signal obtained per bound molecule in the nanoantennas increases by a factor of six, which is promising with respect to the future detection of single molecules. © 2013 The Royal Society of Chemistry.
Source Title: Nanoscale
URI: http://scholarbank.nus.edu.sg/handle/10635/82455
ISSN: 20403364
DOI: 10.1039/c3nr04494g
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