Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/79599
Title: BIOINFORMATICS ANALYSIS OF CYCLIN-DEPENDENT KINASE 5: INSIGHTS TO DRUG DISCOVERY
Authors: KOSARAJU VAMSI KRISHNA
Keywords: cyclin dependent kinase drug discovery
Issue Date: 14-Jan-2013
Source: KOSARAJU VAMSI KRISHNA (2013-01-14). BIOINFORMATICS ANALYSIS OF CYCLIN-DEPENDENT KINASE 5: INSIGHTS TO DRUG DISCOVERY. ScholarBank@NUS Repository.
Abstract: This thesis examines how CDK5 can be targeted in different ways as well as advantages and disadvantages various methods. Methodologies developed in this work definitely throw light on new insights to design CDK5 selective drugs. Various methodologies were applied to understand possibilities of targeting cdk5 such as structural modeling, protein-ligand interactions, structure based drug design, and advanced techniques such as peptide based drug design, design of dynamic blockers. . These computational efforts are expected throw light on designing cdk5 selective inhibitors.
URI: http://scholarbank.nus.edu.sg/handle/10635/79599
Appears in Collections:Ph.D Theses (Open)

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