Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.cbpa.2013.06.005
Title: Target identification of biologically active small molecules via in situ methods
Authors: Su, Y.
Ge, J.
Zhu, B.
Zheng, Y.-G.
Zhu, Q.
Yao, S.Q. 
Issue Date: Oct-2013
Source: Su, Y., Ge, J., Zhu, B., Zheng, Y.-G., Zhu, Q., Yao, S.Q. (2013-10). Target identification of biologically active small molecules via in situ methods. Current Opinion in Chemical Biology 17 (5) : 768-775. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cbpa.2013.06.005
Abstract: The identification of potential cellular targets of small molecules is important in biomedical research and drug discovery, but has been challenging due to a lack of proteome-based methods that enable direct investigation of small molecule-protein interaction in live cells. This review summarizes some of the recent advances in target identification of bioactive molecules (including drugs and natural products) using in situ methods for cell-based proteome profiling of potential on and off targets. © 2013 Elsevier Ltd.
Source Title: Current Opinion in Chemical Biology
URI: http://scholarbank.nus.edu.sg/handle/10635/77661
ISSN: 13675931
DOI: 10.1016/j.cbpa.2013.06.005
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