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|Title:||Target identification of biologically active small molecules via in situ methods|
|Citation:||Su, Y., Ge, J., Zhu, B., Zheng, Y.-G., Zhu, Q., Yao, S.Q. (2013-10). Target identification of biologically active small molecules via in situ methods. Current Opinion in Chemical Biology 17 (5) : 768-775. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cbpa.2013.06.005|
|Abstract:||The identification of potential cellular targets of small molecules is important in biomedical research and drug discovery, but has been challenging due to a lack of proteome-based methods that enable direct investigation of small molecule-protein interaction in live cells. This review summarizes some of the recent advances in target identification of bioactive molecules (including drugs and natural products) using in situ methods for cell-based proteome profiling of potential on and off targets. © 2013 Elsevier Ltd.|
|Source Title:||Current Opinion in Chemical Biology|
|Appears in Collections:||Staff Publications|
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