Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tibtech.2013.01.013
Title: Surface-enhanced Raman scattering in cancer detection and imaging
Authors: Vendrell, M.
Maiti, K.K.
Dhaliwal, K.
Chang, Y.-T. 
Keywords: Diagnostics
Molecular imaging
Nanoparticles
Nanotechnology
Oncology
Translational research
Issue Date: Apr-2013
Source: Vendrell, M., Maiti, K.K., Dhaliwal, K., Chang, Y.-T. (2013-04). Surface-enhanced Raman scattering in cancer detection and imaging. Trends in Biotechnology 31 (4) : 249-257. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tibtech.2013.01.013
Abstract: Technologies that use surface-enhanced Raman scattering (SERS) have experienced significant growth in biomedical research during the past 4 years. In this review we summarize the progress in SERS for cancer diagnostics, including multiplexed detection and identification of new biomarkers, single-nucleotide polymorphisms, and circulating tumor cells. SERS is also used as a non-invasive tool for cancer imaging with immunoSERS microscopy, histological analysis of biopsies, and in vivo detection of tumors. We discuss the future of SERS probes compatible with multiple imaging modalities and their potential for clinical translation (e.g., endoscope-based and intraoperative imaging as tools for surgical guidance). Moreover, we highlight the potential of SERS agents for targeted drug delivery and photothermal therapy. © 2013.
Source Title: Trends in Biotechnology
URI: http://scholarbank.nus.edu.sg/handle/10635/77660
ISSN: 01677799
DOI: 10.1016/j.tibtech.2013.01.013
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